Relationship between office isolated systolic or diastolic hypertension and white-coat hypertension across the age spectrum: a home blood pressure study.

Autor:	Feitosa ADM; Laboratory of Immunopathology Keizo Asami, Federal University of Pernambuco.; Pronto Socorro Cardiológico de Pernambuco (PROCAPE), University of Pernambuco.; MCor, Memorial São José Hospital - Rede D'Or São Luiz, Recife., Mota-Gomes MA; Department of Internal Medicine, State University of Health Sciences of Alagoas.; CESMAC University Center, Maceió., Barroso WS; Hypertension League, Federal University of Goiás, Goiânia., Miranda RD; Geriatrics Division, Federal University of São Paulo, São Paulo., Barbosa ECD; Hypertension League of Porto Alegre, Porto Alegre., Pedrosa RP; Pronto Socorro Cardiológico de Pernambuco (PROCAPE), University of Pernambuco.; MCor, Memorial São José Hospital - Rede D'Or São Luiz, Recife., Oliveira PC; RealCor, Royal Portuguese Hospital of Charity in Pernambuco, Recife., Feltosa CLDM; Pronto Socorro Cardiológico de Pernambuco (PROCAPE), University of Pernambuco., Brandão AA; School of Medicine, State University of Rio de Janeiro, Rio de Janeiro., Lima-Filho JL; Laboratory of Immunopathology Keizo Asami, Federal University of Pernambuco., Sposito AC; Department of Internal Medicine, School of Medical Sciences, State University of Campinas, Campinas, Brazil., Coca A; Hypertension and Vascular Risk Unit, Department of Internal Medicine, Hospital Clínic (IDIBAPS) Effect, University of Barcelona, Barcelona, Spain., Nadruz W Jr; Laboratory of Immunopathology Keizo Asami, Federal University of Pernambuco.; Department of Internal Medicine, School of Medical Sciences, State University of Campinas, Campinas, Brazil.
Jazyk:	angličtina
Zdroj:	Journal of hypertension [J Hypertens] 2020 Apr; Vol. 38 (4), pp. 663-670.
DOI:	10.1097/HJH.0000000000002320
Abstrakt:	Objective: The current study investigated the prevalence of white-coat hypertension (WCH) and white-coat uncontrolled hypertension (WUCH) throughout the age spectrum among individuals with office isolated systolic hypertension (ISH), isolated diastolic hypertension (IDH) and systolic-diastolic hypertension (SDH) who were untreated or treated with antihypertensive medications, respectively. Methods: We cross-sectionally evaluated 8809 untreated (42% males, 52.1 ± 16.2 years) and 9136 treated (39% males, 59.7 ± 14.5 years) individuals from two independent Brazilian populations who underwent home blood pressure monitoring. Participants were also categorized as younger (<40 years), intermediate (≥40 and <60 years) and older (≥60 years) age. Results: Unadjusted and adjusted analyses showed that the frequency of WCH and WUCH was significantly greater (P < 0.05) in ISH and IDH than SDH at all age groups. Logistic regression analysis adjusted for sex, BMI and studied population showed that, compared with SDH, ISH had in average 4.1, 3.1 and 1.6-fold greater risk of WCH and 3.3, 3.6 and 2.0-fold greater risk of WUCH at younger, intermediate and older ages, whereas IDH had in average 2.3, 2.6 and 2.0-fold greater risk of WCH and 3.8, 3.2 and 3.8-fold greater risk of WUCH at younger, intermediate and older ages, respectively. Conclusion: ISH and IDH were associated with higher prevalence of WCH and WUCH than SDH across all age spectrum. In addition, treated and untreated ISH individuals with age less than 60 years and treated IDH individuals of all ages had the highest risk of having WCH phenotypes.
Databáze:	MEDLINE
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