What have we learned from transplanting older patients?

Autor: Varadarajan I; University of Virginia Cancer Center, 1300 Jefferson Park Avenue, Charlottesville, VA, 22908, USA., Ballen KK; University of Virginia Cancer Center, 1300 Jefferson Park Avenue, Charlottesville, VA, 22908, USA. Electronic address: KB3TC@hscmail.mcc.virginia.edu.
Jazyk: angličtina
Zdroj: Best practice & research. Clinical haematology [Best Pract Res Clin Haematol] 2019 Dec; Vol. 32 (4), pp. 101110. Date of Electronic Publication: 2019 Oct 18.
DOI: 10.1016/j.beha.2019.101110
Abstrakt: Aggressive curative therapies have now been extended to patients older than 65 years, a fast-growing segment of the population. As the number of allogeneic transplants in patients older than age 65 is increasing, attention is now focused on improving outcomes in this group. This paper discusses important aspects of allogeneic transplant in the older patient, focusing on donor and patient selection, choice of conditioning regimen and graft source, and the importance of timely access to a transplant center.
(Copyright © 2019 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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