| Autor: |
Roerdink SJ; Elisabeth-TweeSteden Ziekenhuis, Afd. Psychiatrie, Tilburg.; Contact: S.J. Roerdink (sharleen.roerdink@gmail.com)., Veth CPM; Elisabeth-TweeSteden Ziekenhuis,Afd. Psychiatrie, Tilburg., van Pamelen J; Elisabeth-TweeSteden Ziekenhuis, Afd. Neurologie, Tilburg., Manuputty J; Elisabeth-TweeSteden Ziekenhuis, Afd. Neurologie, Tilburg., Swolfs SN; Elisabeth-TweeSteden Ziekenhuis, Afd. Psychiatrie, Tilburg. |
| Jazyk: |
Dutch; Flemish |
| Zdroj: |
Nederlands tijdschrift voor geneeskunde [Ned Tijdschr Geneeskd] 2019 Nov 14; Vol. 163. Date of Electronic Publication: 2019 Nov 14. |
| Abstrakt: |
A 60-year-old woman was admitted to the medical psychiatric unit with neurological and psychiatric symptoms. She was being treated with a maintenance dose of lithium for bipolar I disorder. Lithium toxicity and manic state were both considered. However, serum lithium levels appeared to be non-toxic. During hospital admission, her symptoms worsened and many diagnostic tests were performed. Lithium toxicity was considered again and lithium was discontinued, despite therapeutic blood levels. The neuro-psychiatric symptoms subsequently disappeared and the patient improved without residual symptoms. When neuro-psychiatric symptoms occur without elevated lithium levels, the possibility of chronic lithium toxicity should still be considered. More caution is required when risk factors are present, such as: old age, interacting medication, reduced renal function, dehydration and fever. Finally, electroencephalography can contribute to the diagnosis of chronic lithium toxicity. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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