HISTONE DEACETYLASE 9 stimulates auxin-dependent thermomorphogenesis in Arabidopsis thaliana by mediating H2A.Z depletion.

Autor:	van der Woude LC; Molecular Plant Physiology, Institute of Environmental Biology, Utrecht University, 3584 CH Utrecht, The Netherlands., Perrella G; Institute of Molecular, Cell & Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, G12 8QQ Glasgow, United Kingdom.; Trisaia Research Centre, Italian National Agency for New Technologies, Energy and Sustainable Economic Development, 75026 Rotondella (Matera), Italy., Snoek BL; Theoretical Biology and Bioinformatics, Institute of Biodynamics and Biocomplexity, Utrecht University, 3584 CH Utrecht, The Netherlands., van Hoogdalem M; Laboratory of Plant Physiology, Wageningen University, 6708 PB Wageningen, The Netherlands., Novák O; Umeå Plant Science Centre, Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, SE-901 83 Umeå, Sweden.; Laboratory of Growth Regulators, Institute of Experimental Botany, The Czech Academy of Sciences & Faculty of Science, Palacký University, 78371 Olomouc, Czech Republic., van Verk MC; Theoretical Biology and Bioinformatics, Institute of Biodynamics and Biocomplexity, Utrecht University, 3584 CH Utrecht, The Netherlands.; Plant Microbe Interactions, Institute of Environmental Biology, Utrecht University, 3584 CH Utrecht, The Netherlands., van Kooten HN; Molecular Plant Physiology, Institute of Environmental Biology, Utrecht University, 3584 CH Utrecht, The Netherlands., Zorn LE; Molecular Plant Physiology, Institute of Environmental Biology, Utrecht University, 3584 CH Utrecht, The Netherlands., Tonckens R; Molecular Plant Physiology, Institute of Environmental Biology, Utrecht University, 3584 CH Utrecht, The Netherlands., Dongus JA; Molecular Plant Physiology, Institute of Environmental Biology, Utrecht University, 3584 CH Utrecht, The Netherlands., Praat M; Molecular Plant Physiology, Institute of Environmental Biology, Utrecht University, 3584 CH Utrecht, The Netherlands., Stouten EA; Molecular Plant Physiology, Institute of Environmental Biology, Utrecht University, 3584 CH Utrecht, The Netherlands., Proveniers MCG; Molecular Plant Physiology, Institute of Environmental Biology, Utrecht University, 3584 CH Utrecht, The Netherlands., Vellutini E; Institute of Molecular, Cell & Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, G12 8QQ Glasgow, United Kingdom., Patitaki E; Institute of Molecular, Cell & Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, G12 8QQ Glasgow, United Kingdom., Shapulatov U; Laboratory of Plant Physiology, Wageningen University, 6708 PB Wageningen, The Netherlands., Kohlen W; Laboratory of Molecular Biology, Wageningen University, 6708 PB Wageningen, The Netherlands., Balasubramanian S; School of Biological Sciences, Monash University, VIC 3800, Melbourne, Australia., Ljung K; Umeå Plant Science Centre, Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, SE-901 83 Umeå, Sweden., van der Krol AR; Laboratory of Plant Physiology, Wageningen University, 6708 PB Wageningen, The Netherlands., Smeekens S; Molecular Plant Physiology, Institute of Environmental Biology, Utrecht University, 3584 CH Utrecht, The Netherlands., Kaiserli E; Institute of Molecular, Cell & Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, G12 8QQ Glasgow, United Kingdom., van Zanten M; Molecular Plant Physiology, Institute of Environmental Biology, Utrecht University, 3584 CH Utrecht, The Netherlands; m.vanzanten@uu.nl.
Jazyk:	angličtina
Zdroj:	Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2019 Dec 10; Vol. 116 (50), pp. 25343-25354. Date of Electronic Publication: 2019 Nov 25.
DOI:	10.1073/pnas.1911694116
Abstrakt:	Many plant species respond to unfavorable high ambient temperatures by adjusting their vegetative body plan to facilitate cooling. This process is known as thermomorphogenesis and is induced by the phytohormone auxin. Here, we demonstrate that the chromatin-modifying enzyme HISTONE DEACETYLASE 9 (HDA9) mediates thermomorphogenesis but does not interfere with hypocotyl elongation during shade avoidance. HDA9 is stabilized in response to high temperature and mediates histone deacetylation at the YUCCA8 locus, a rate-limiting enzyme in auxin biosynthesis, at warm temperatures. We show that HDA9 permits net eviction of the H2A.Z histone variant from nucleosomes associated with YUCCA8 , allowing binding and transcriptional activation by PHYTOCHROME INTERACTING FACTOR 4, followed by auxin accumulation and thermomorphogenesis. Competing Interests: The authors declare no competing interest.
Databáze:	MEDLINE
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