Periodontal disease: Repercussions in pregnant woman and newborn health-A cohort study.

Autor: Figueiredo MGOP; Pediatrics Department, Botucatu Medical School, São Paulo State University (UNESP),Botucatu city, São Paulo State, Brazil., Takita SY; Pediatrics Department, Botucatu Medical School, São Paulo State University (UNESP),Botucatu city, São Paulo State, Brazil., Dourado BMR; Pediatrics Department, Botucatu Medical School, São Paulo State University (UNESP),Botucatu city, São Paulo State, Brazil., Mendes HS; Botucatu Clinics Hospital, Botucatu city, São Paulo State, Brazil., Terakado EO; Psychology Department, Paulista University (UNIP), São Paulo city, São Paulo State, Brazil., Nunes HRC; Pediatrics Department, Botucatu Medical School, São Paulo State University (UNESP),Botucatu city, São Paulo State, Brazil., Fonseca CRBD; Pediatrics Department, Botucatu Medical School, São Paulo State University (UNESP),Botucatu city, São Paulo State, Brazil.
Jazyk: angličtina
Zdroj: PloS one [PLoS One] 2019 Nov 22; Vol. 14 (11), pp. e0225036. Date of Electronic Publication: 2019 Nov 22 (Print Publication: 2019).
DOI: 10.1371/journal.pone.0225036
Abstrakt: Objective: To investigate the repercussion of periodontal disease (PD) in the pregnant woman health and the complications during pregnancy and delivery, as well as negative outcomes for the newborn (as infections, prematurity, low birth weight and fetal growth restriction).
Method: Retrospective cohort study, based on medical records of 142 pregnant women assisted at a prenatal service of usual risk between 2012-2014, with a dental evaluation for PD. Maternal variables, along with labor and newborn variables, were analyzed. The newborns were stratified into two groups: offspring of mothers with PD (subdivided into Severe Periodontal Disease-SPD) and offspring of mothers without PD. Each outcome was adjusted by a multiple logistic regression model, with significance for p-value <0.05, considering all potential confounding factors.
Results: Among women diagnosed with SPD, the odds ratio for vulvovaginitis was 3.45 times greater (OR = 3.45, p-value = 0.050) and 5.59 times higher for premature rupture of membranes (OR = 5.59; p-value = 0.017). For neonates, the chance of fetal growth restriction was 11.53 times higher for pregnant women with SPD (OR = 11.53, p = 0.041).
Conclusion: The periodontal disease increased the chance of neonatal and maternal negative outcomes, being the fetal growth restriction, vulvovaginitis and premature rupture of the membrane (PROM) the main results driven by the presence of Severe Periodontal Disease.
Competing Interests: The authors have declared that no competing interests exist.
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje