Isolated posterior fossa involvement of progressive multifocal leucoencephalopathy in HIV: A case series with review of the literature.

Autor: Mudau A; Department of Radiology, University of Pretoria, South Africa., Suleman FE; Department of Radiology, University of Pretoria, South Africa., Schutte CM; Department of Neurology, University of Pretoria, South Africa., Lockhat ZI; Department of Radiology, University of Pretoria, South Africa.
Jazyk: angličtina
Zdroj: SA journal of radiology [SA J Radiol] 2017 Nov 14; Vol. 21 (2), pp. 1262. Date of Electronic Publication: 2017 Nov 14 (Print Publication: 2017).
DOI: 10.4102/sajr.v21i2.1262
Abstrakt: Progressive multifocal leucoencephalopathy (PML) is a progressive demyelinating condition resulting from infection with the John Cunningham virus and precipitated by immunocompromised states. The HIV pandemic, especially in sub-Saharan Africa, has resulted in an increase in the number of patients presenting with PML. Imaging plays an important role in diagnosis and the distribution of the disease is predominantly supratentorial. Isolated posterior fossa involvement is a rare finding with very few cases described in the literature. We present the largest case series of patients described in the literature, with isolated posterior fossa involvement of PML, in HIV-positive patients.
Competing Interests: The authors declare they have no personal or financial relationship which may have influenced them in writing this article.
(© 2017. The Authors.)
Databáze: MEDLINE