The impact of interpregnancy weight change on perinatal outcomes in women and their children: A systematic review and meta-analysis.

Autor: Timmermans YEG; Department of Pediatrics, Maastricht University Medical Centre (MUMC+), Maastricht, The Netherlands.; School for Oncology and Developmental Biology (GROW), Maastricht University, Maastricht, The Netherlands., van de Kant KDG; Department of Pediatrics, Maastricht University Medical Centre (MUMC+), Maastricht, The Netherlands.; School for Public Health and Primary Health Care (CAPHRI), Department of Family Medicine, Maastricht University, Maastricht, The Netherlands., Oosterman EO; Department of Pediatrics, Maastricht University Medical Centre (MUMC+), Maastricht, The Netherlands., Spaanderman MEA; School for Oncology and Developmental Biology (GROW), Maastricht University, Maastricht, The Netherlands.; Department of Gynecology and Obstetrics, Maastricht University Medical Centre (MUMC+), Maastricht, The Netherlands., Villamor-Martinez E; Department of Pediatrics, Maastricht University Medical Centre (MUMC+), Maastricht, The Netherlands.; School for Oncology and Developmental Biology (GROW), Maastricht University, Maastricht, The Netherlands., Kleijnen J; School for Public Health and Primary Health Care (CAPHRI), Department of Family Medicine, Maastricht University, Maastricht, The Netherlands., Vreugdenhil ACE; Department of Pediatrics, Maastricht University Medical Centre (MUMC+), Maastricht, The Netherlands.; School of Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, Maastricht, The Netherlands.
Jazyk: angličtina
Zdroj: Obesity reviews : an official journal of the International Association for the Study of Obesity [Obes Rev] 2020 Mar; Vol. 21 (3), pp. e12974. Date of Electronic Publication: 2019 Nov 21.
DOI: 10.1111/obr.12974
Abstrakt: Prepregnancy overweight and obesity are associated with higher risk of perinatal complications. However, the effect of weight change prior to pregnancy on perinatal outcome is largely unknown. Therefore, it is aimed to examine the impact on perinatal outcomes of interpregnancy BMI change in women of different BMI categories. The MEDLINE, EMBASE, LILACS, and CINAHL databases were searched (1990-August 2019). Observational studies on interpregnancy BMI change were selected. Outcomes evaluated were gestational diabetes mellitus (GDM), preeclampsia, gestational hypertension (GH), cesarean section, preterm birth, and newborns being large (LGA) or small (SGA) for gestational age. Meta-analyses and meta-regression analyses were executed. Thirty studies were included (n > 1 million). Interpregnancy BMI gain was associated with a higher risk of GDM (for BMI gain ≥3 kg/m 2 : OR 2.21; [95%CI 1.53-3.19]), preeclampsia (1.77 [1.53-2.04]), GH (1.78 [1.61-1.97]), cesarean section (1.32 [1.24-1.39]), and LGA (1.54 [1.28-1.86]). The effects of BMI gain were most pronounced in women with BMI <25 kg/m 2 before the first pregnancy regarding GDM, GH, and cesarean section. Except for LGA, interpregnancy BMI loss did not result in a decreased risk of perinatal complications. In this study, women of normal weight who gain weight before pregnancy were identified as a high-risk population for perinatal complications. This emphasizes that weight management is important for women of all BMI categories and a pregnancy wish.
(© 2019 The Authors. Obesity Reviews published by John Wiley & Sons Ltd on behalf of World Obesity Federation.)
Databáze: MEDLINE
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