Effect of Diets with Different Lipid's Sources On Serum and Brain Fatty Acids Profile: Experimental Model.

Autor: Slobodianik NH; Department of Nutrition, The University of Buenos Aires, Faculty of Pharmacy and Biochemistry, Buenos Aires, Argentina., Perris PD; Department of Nutrition, The University of Buenos Aires, Faculty of Pharmacy and Biochemistry, Buenos Aires, Argentina., Mambrin MC; Department of Nutrition, The University of Buenos Aires, Faculty of Pharmacy and Biochemistry, Buenos Aires, Argentina., Fernandez I; Department of Nutrition, The University of Buenos Aires, Faculty of Pharmacy and Biochemistry, Buenos Aires, Argentina., Feliu MS; Department of Nutrition, The University of Buenos Aires, Faculty of Pharmacy and Biochemistry, Buenos Aires, Argentina.
Jazyk: angličtina
Zdroj: Endocrine, metabolic & immune disorders drug targets [Endocr Metab Immune Disord Drug Targets] 2020; Vol. 20 (4), pp. 625-631.
DOI: 10.2174/1871530319666191120114032
Abstrakt: Background: The importance of diet in health is widely accepted and recognized. Diet lipid profile is important to prevent chronic diseases and improve the quality of an individual's life.
Objective: The objective of this report is to analyze the effect of different sources of dietary lipids with standard and high concentration on growing rats.
Methods: Experimental diets contained 15 or 42% kcal of fat, provided by butter (B), olive oil (O), high oleic sunflower oil (HO), and sunflower oil (S). Control diet (C) was normocaloric with 15% kcal of fat provided by soy oil. All diets were complete in the other nutrients according to AIN 1993 and were administered for 40 days.
Results: Daily intake was similar in all groups. The administration of these diets provoked changes in serum fatty acid profile in response to the different sources of dietary lipids used; no changes were observed in the brain´s fatty acids.
Conclusion: These results would suggest that the organism tries first to supply the brain´s fatty acid needs at the expense of its modification in serum.
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Databáze: MEDLINE