Behavioral Responses to Uncertainty in Weight-Restored Anorexia Nervosa - Preliminary Results.

Autor:	Piccolo M; Unit of Clinical and Health Psychology, University of Fribourg, Fribourg, Switzerland., Milos GF; Department of Consultation-Liaison-Psychiatry and Psychosomatic Medicine, University Hospital Zurich, Zurich, Switzerland., Bluemel S; Division of Gastroenterology and Hepatology, University Hospital Zurich, Zurich, Switzerland., Schumacher S; Department of Consultation-Liaison-Psychiatry and Psychosomatic Medicine, University Hospital Zurich, Zurich, Switzerland., Mueller-Pfeiffer C; Department of Consultation-Liaison-Psychiatry and Psychosomatic Medicine, University Hospital Zurich, Zurich, Switzerland., Fried M; Division of Gastroenterology and Hepatology, University Hospital Zurich, Zurich, Switzerland.; Zurich Center for Integrative Human Physiology, Zurich, Switzerland., Ernst M; Section on Neurobiology of Fear and Anxiety, National Institute of Mental Health (NIMH), Bethesda, MD, United States., Martin-Soelch C; Unit of Clinical and Health Psychology, University of Fribourg, Fribourg, Switzerland.
Jazyk:	angličtina
Zdroj:	Frontiers in psychology [Front Psychol] 2019 Nov 05; Vol. 10, pp. 2492. Date of Electronic Publication: 2019 Nov 05 (Print Publication: 2019).
DOI:	10.3389/fpsyg.2019.02492
Abstrakt:	Impaired decision-making under conditions of uncertainty seems to contribute to the expression and maintenance of anorexia nervosa (AN), but it is not clear whether this impairment is a disease state that would remit with treatment, or a persisting trait in patients with AN. To examine this question, a longitudinal study was conducted in 12 female inpatients with AN (age M = 22.2, SE = 1.36), before (Time-1) and after reaching a body mass index of >17.5 kg/m 2 (Time-2). Intolerance of uncertainty (IU) was assessed via a decision-making task, the wheel of fortune (WOF). Weight gain at Time-2 was accompanied with significant changes in uncertainty-related performance compared to Time-1 [(Time × Uncertainty), p < 0.05]. At Time-1, reaction times (RTs) varied in function of uncertainty, while at Time-2, uncertainty did not modulate RTs. These findings support a change in decision-making under uncertainty with successful weight-rehabilitation in AN. While IU was present in underweight patients, it became non-significant after weight restoration. (Copyright © 2019 Piccolo, Milos, Bluemel, Schumacher, Mueller-Pfeiffer, Fried, Ernst and Martin-Soelch.)
Databáze:	MEDLINE
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