Outcomes of Cases of Prenatally-Diagnosed Congenital Pulmonary Airway Malformation.

Autor: Beksac MS; Division of Perinatology, Department of Obstetrics and Gynecology, Hacettepe University, Ankara, Turkey., Fadiloglu E; Division of Perinatology, Department of Obstetrics and Gynecology, Hacettepe University, Ankara, Turkey., Tanacan A; Division of Perinatology, Department of Obstetrics and Gynecology, Hacettepe University, Ankara, Turkey., Unal C; Division of Perinatology, Department of Obstetrics and Gynecology, Hacettepe University, Ankara, Turkey., Tepe NB; Division of Perinatology, Department of Obstetrics and Gynecology, Hacettepe University, Ankara, Turkey., Aydın E; Division of Perinatology, Department of Obstetrics and Gynecology, Hacettepe University, Ankara, Turkey., Orgul G; Division of Perinatology, Department of Obstetrics and Gynecology, Hacettepe University, Ankara, Turkey., Yurdakok M; Division of Neonatology, Department of Pediatrics, Hacettepe University, Ankara, Turkey.
Jazyk: angličtina
Zdroj: Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia [Rev Bras Ginecol Obstet] 2019 Nov; Vol. 41 (11), pp. 654-659. Date of Electronic Publication: 2019 Nov 19.
DOI: 10.1055/s-0039-1697983
Abstrakt: Objective:  To evaluate the outcomes of cases of prenatally-diagnosed congenital pulmonary airway malformation (CPAM).
Methods:  We retrospectively evaluated cases of prenatally-diagnosed CPAM between 2004 and 2018. Ultrasonographic features such as visualization of a fetal lung mass and heterogeneous pulmonary parenchyma were used for CPAM diagnosis. Prenatal and postnatal findings were compared in terms of accuracy regarding the CPAM diagnosis.
Results:  The sample consisted of 27 cases. There were four cases in which the patients opted for the termination of pregnancy due to the severity of the lesion. A total of 23 neonates were delivered, and CPAM was confirmed in 15 cases. The median gestational age at delivery was 37 weeks (28-40 weeks) and the mean birth weight was 2,776 g. There were two neonatal deaths, one due to pneumothorax, and the other due to hypoplastic left heart syndrome (HLHS). A total of five patients with respiratory problems were operated in the postpartum period. There were eight misdiagnosis: bronchopulmonary sequestration (five cases), congenital lobar emphysema (two cases), and congenital diaphragm hernia (one case).
Conclusion:  A precise postnatal diagnosis is very important to organize the proper management of the pregnancies with fetuses with CPAM. The positive predictive value of the prenatal diagnosis of CPAM via ultrasonography is of 70.3%. The differential diagnosis of CPAM may be prolonged to the postpartum period in some cases.
Competing Interests: The authors have none to declare.
(Thieme Revinter Publicações Ltda Rio de Janeiro, Brazil.)
Databáze: MEDLINE