Eosinophilic Fasciitis Responds Well to Steroids and Methotrexate.

Autor: Mahdi AS; Department of Medicine, Rheumatology Unit, Royal Hospital, Muscat, Oman., Nasr IH; Immunology Department, Royal Hospital, Muscat, Oman., Al Jahdhami S; Histopathology Department, Sultan Qaboos University Hospital, Muscat, Oman., Kamona A; Radiology Department, Royal Hospital, Muscat, Oman., Al Wahshi HA; Department of Medicine, Rheumatology Unit, Royal Hospital, Muscat, Oman.
Jazyk: angličtina
Zdroj: Oman medical journal [Oman Med J] 2019 Nov; Vol. 34 (6), pp. 564-567.
DOI: 10.5001/omj.2019.102
Abstrakt: Eosinophilic fasciitis (EF) is a rare systemic inflammatory disease with an unknown etiology. Making a diagnosis in such a case is always a challenge as it is a rare disease and mimics scleroderma and scleroderma-like syndrome but should be kept in mind as it carries a high mortality. Furthermore, it is a treatable disease. Here, we report a 41-year-old woman who presented to the rheumatology clinic at the Royal Hospital, Muscat, Oman, with a one-month history of bilateral swelling of the forearms along with skin tightness and fingers contraction. Her history and physical examination along with histopathological examination and magnetic resonance imaging findings were consistent with EF. She showed an excellent response to steroids and methotrexate which is not a combination therapy that has been tried or mentioned previously.
(The OMJ is Published Bimonthly and Copyrighted 2019 by the OMSB.)
Databáze: MEDLINE