Effect of Endomorphin-1 on Contractile Activity of Rat Mesenteric Lymphatic Vessels.

Autor: Nechaykina OV; Research Institute of Hygiene, Occupational Pathology, and Human Ecology, Federal Medical-Biological Agency of Russia, Kuzmolovsky, Leningrad Region, Russia. olga2278@mail.ru., Petunov SG; Research Institute of Hygiene, Occupational Pathology, and Human Ecology, Federal Medical-Biological Agency of Russia, Kuzmolovsky, Leningrad Region, Russia.
Jazyk: angličtina
Zdroj: Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2019 Nov; Vol. 168 (1), pp. 55-57. Date of Electronic Publication: 2019 Nov 19.
DOI: 10.1007/s10517-019-04645-3
Abstrakt: We studied the effect of endomorphin-1 on isolated mesenteric lymphatic vessels in rats. It was found that endomorphin-1 caused a dose-dependent increase in the contractile activity of lymphangions, which was associated with stimulation of intracellular calcium depots. The observed effect of endomorphin-1 in isolated lymphatic vessels has a complex mechanism; it depends on the concentration of the applied peptide and is probably determined by its interaction with non-opioid receptors.
Databáze: MEDLINE
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