The cingulate cortex and spatial neglect.

Autor:	Barrett AM; Center for Stroke Rehabilitation Research, Kessler Foundation, West Orange, NJ, United States; Kessler Institute for Rehabilitation, West Orange, NJ, United States; Department of Physical Medicine and Rehabilitation, Rutgers New Jersey Medical School, Newark, NJ, United States. Electronic address: abarrett@kesslerfoundation.org., Abdou A; Center for Stroke Rehabilitation Research, Kessler Foundation, West Orange, NJ, United States; Burke Rehabilitation Hospital, Mamaroneck, NY, United States; Montefiore Health System, Bronx, NY, United States., Caulfield MD; Department of Physical Medicine and Rehabilitation, Rutgers New Jersey Medical School, Newark, NJ, United States; Department of Psychological and Brain Sciences, Villanova University, Villanova, PA, United States.
Jazyk:	angličtina
Zdroj:	Handbook of clinical neurology [Handb Clin Neurol] 2019; Vol. 166, pp. 129-150.
DOI:	10.1016/B978-0-444-64196-0.00009-1
Abstrakt:	Spatial neglect is asymmetric attention, orienting, and action causing functional disability. It is linked to higher-order cortical sensory processing; however, spatial motor "Aiming" processing is critical to fundamental, adaptive environmental movement and daily life function. The cingulate cortex, in particular the anterior cingulate and anterior midcingulate cortex, is strongly linked to spatial Aiming deficits and likely to predict daily life disability in spatial neglect. The authors review the impact and mechanisms of spatial neglect and then describe specific symptoms associated with spatial neglect that are theoretically linked to cingulate cortical functions or associated with lesions extending to cingulate regions in a well-characterized spatial neglect cohort. The treatment implications for a link between cingulate cortex spatial Aiming neglect and therapies that improve spatial action, arousal, and persistence are discussed. Clinicians may want to consider theoretically motivated treatments targeted at specific symptoms as well as use treatments supported for spatial neglect based on unselected and uncharacterized groups. (Copyright © 2019 Elsevier B.V. All rights reserved.)
Databáze:	MEDLINE
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