| Autor: |
Dimmitt SB; Department of Medicine, University of Western Australia, Royal Perth Hospital., Beilin LJ, Hockings BE |
| Jazyk: |
angličtina |
| Zdroj: |
The Medical journal of Australia [Med J Aust] 1988 Aug 15; Vol. 149 (4), pp. 218. |
| DOI: |
10.5694/j.1326-5377.1988.tb120577.x |
| Abstrakt: |
Verapamil is an effective and relatively-safe antihypertensive drug. Serious adverse effects are uncommon and mainly have been related to the depression of cardiac contractility and conduction, especially when the drug is combined with beta-blocking agents. We report a case in which myocardial infarction coincided with the introduction of captopril and the withdrawal of verapamil in a previously asymptomatic woman with severe hypertension. Possible mechanisms that involve a verapamil-related increase in platelet and/or vascular alpha 2-adrenoreceptor affinity for catecholamines are discussed. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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