EML1-ABL1 Is Activated by Coiled-Coil-Mediated Oligomerization and Induces T-Cell Acute Lymphoblastic Leukemia or Myeloproliferative Disease in a Mouse Bone Marrow Transplant Model.

Autor: Vanden Bempt M; VIB Center for Cancer Biology, Leuven, Belgium.; KU Leuven Center for Human Genetics, Leuven, Belgium.; LKI-Leuven Cancer Institute, Leuven, Belgium., Mentens N; VIB Center for Cancer Biology, Leuven, Belgium.; KU Leuven Center for Human Genetics, Leuven, Belgium.; LKI-Leuven Cancer Institute, Leuven, Belgium., Vandenberghe P; KU Leuven Center for Human Genetics, Leuven, Belgium.; LKI-Leuven Cancer Institute, Leuven, Belgium.; KU Leuven, Department of Hematology, Leuven, Belgium., Cools J; VIB Center for Cancer Biology, Leuven, Belgium.; KU Leuven Center for Human Genetics, Leuven, Belgium.; LKI-Leuven Cancer Institute, Leuven, Belgium., De Keersmaecker K; LKI-Leuven Cancer Institute, Leuven, Belgium.; KU Leuven, Department of Oncology, Leuven, Belgium.
Jazyk: angličtina
Zdroj: HemaSphere [Hemasphere] 2018 Mar 06; Vol. 2 (2), pp. e32. Date of Electronic Publication: 2018 Mar 06 (Print Publication: 2018).
DOI: 10.1097/HS9.0000000000000032
Abstrakt: Supplemental Digital Content is available in the text.
Competing Interests: The authors have indicated they have no potential conflicts of interest to disclose.
(Copyright © 2018 the Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the European Hematology Association.)
Databáze: MEDLINE
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