A Standard Numbering Scheme for Class C β-Lactamases.

Autor:	Mack AR; Department of Molecular Biology and Microbiology, Case Western Reserve University, Cleveland, Ohio, USA.; Research Service, Louis Stokes Cleveland Department of Veterans Affairs, Cleveland, Ohio, USA., Barnes MD; Department of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.; Research Service, Louis Stokes Cleveland Department of Veterans Affairs, Cleveland, Ohio, USA., Taracila MA; Department of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.; Research Service, Louis Stokes Cleveland Department of Veterans Affairs, Cleveland, Ohio, USA., Hujer AM; Department of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.; Research Service, Louis Stokes Cleveland Department of Veterans Affairs, Cleveland, Ohio, USA., Hujer KM; Department of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.; Research Service, Louis Stokes Cleveland Department of Veterans Affairs, Cleveland, Ohio, USA., Cabot G; Red Española de Investigación en Patología Infecciosa (REIPI), Instituto de Salud Carlos III, Madrid, Spain.; Servicio de Microbiología, Hospital Universitario Son Espases, Instituto de Investigación Sanitaria Illes Balears (IdISBa), Palma de Mallorca, Spain., Feldgarden M; National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, USA., Haft DH; National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, USA., Klimke W; National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, USA., van den Akker F; Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio, USA., Vila AJ; CWRU-Cleveland VAMC Center for Antimicrobial Resistance and Epidemiology (Case VA CARES), Cleveland, Ohio, USA.; Instituto de Biología Molecular y Celular de Rosario (IBR, CONICET-UNR), Rosario, Argentina.; Plataforma Argentina de Biología Estructural y Metabolómica PLABEM, Buenos Aires, Argentina.; Área Biofísica, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Rosario, Argentina., Smania A; Centro de Investigaciones en Química Biológica de Córodoba (CIQUIBIC), CONICET, Universidad Nacional de Córdoba, Córdoba, Argentina.; Departamento de Química Biológica Ranwel Caputto, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina., Haider S; UCL School of Pharmacy, University College London, London, United Kingdom., Papp-Wallace KM; Department of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.; Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio, USA.; Department of Proteomics and Bioinformatics, Case Western Reserve University, Cleveland, Ohio, USA.; Research Service, Louis Stokes Cleveland Department of Veterans Affairs, Cleveland, Ohio, USA., Bradford PA; Antimicrobial Development Specialists, LLC, Nyack, New York, USA., Rossolini GM; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.; Microbiology and Virology Unit, Florence Careggi University Hospital, Florence, Italy., Docquier JD; Department of Medical Biotechnology, University of Siena, Siena, Italy., Frère JM; Centre for Protein Engineering (CIP), University of Liège, Liège, Belgium., Galleni M; Centre for Protein Engineering (CIP), University of Liège, Liège, Belgium., Hanson ND; Department of Microbiology and Immunology, Creighton School of Medicine, Omaha, Nebraska, USA., Oliver A; Red Española de Investigación en Patología Infecciosa (REIPI), Instituto de Salud Carlos III, Madrid, Spain.; Servicio de Microbiología, Hospital Universitario Son Espases, Instituto de Investigación Sanitaria Illes Balears (IdISBa), Palma de Mallorca, Spain., Plésiat P; Laboratoire de Bactériologie, Centre Hospitalier Régional Universitaire, Besançon, France.; UMR6249 CNRS Chrono-Environnement, Université de Bourgogne Franche-Comté, Besançon, France.; Centre National de Référence de la Résistance aux Antibiotiques, Besançon, France., Poirel L; Emerging Antibiotic Resistance Unit, Medical and Molecular Microbiology, Faculty of Science and Medicine, University of Fribourg, Fribourg, Switzerland.; Swiss National Reference Center for Emerging Antibiotic Resistance (NARA), University of Fribourg, Fribourg, Switzerland., Nordmann P; Emerging Antibiotic Resistance Unit, Medical and Molecular Microbiology, Faculty of Science and Medicine, University of Fribourg, Fribourg, Switzerland.; Swiss National Reference Center for Emerging Antibiotic Resistance (NARA), University of Fribourg, Fribourg, Switzerland., Palzkill TG; Department of Pharmacology and Chemical Biology, Baylor College of Medicine, Houston, Texas, USA.; Verna Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas, USA., Jacoby GA; Lahey Hospital and Medical Center, Burlington, Massachusetts, USA., Bush K; Department of Biology, Indiana University Bloomington, Bloomington, Indiana, USA., Bonomo RA; Department of Molecular Biology and Microbiology, Case Western Reserve University, Cleveland, Ohio, USA robert.bonomo@va.gov.; Department of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.; Department of Pharmacology, Case Western Reserve University, Cleveland, Ohio, USA.; Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio, USA.; Department of Proteomics and Bioinformatics, Case Western Reserve University, Cleveland, Ohio, USA.; Research Service, Louis Stokes Cleveland Department of Veterans Affairs, Cleveland, Ohio, USA.; CWRU-Cleveland VAMC Center for Antimicrobial Resistance and Epidemiology (Case VA CARES), Cleveland, Ohio, USA.; Geriatric Research Education and Clinical Centers (GRECC), Louis Stokes Cleveland Department of Veterans Affairs, Cleveland, Ohio, USA.
Jazyk:	angličtina
Zdroj:	Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2020 Feb 21; Vol. 64 (3). Date of Electronic Publication: 2020 Feb 21 (Print Publication: 2020).
DOI:	10.1128/AAC.01841-19
Abstrakt:	Unlike for classes A and B, a standardized amino acid numbering scheme has not been proposed for the class C (AmpC) β-lactamases, which complicates communication in the field. Here, we propose a scheme developed through a collaborative approach that considers both sequence and structure, preserves traditional numbering of catalytically important residues (Ser 64 , Lys 67 , Tyr 150 , and Lys 315 ), is adaptable to new variants or enzymes yet to be discovered and includes a variation for genetic and epidemiological applications. (Copyright © 2020 American Society for Microbiology.)
Databáze:	MEDLINE
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