Effects of starvation and refeeding cycles on spermatogenesis and sex steroids in the Nile tilapia Oreochromis niloticus.

Autor: Sales CF; Departamento de Morfologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, 31270-901, Belo Horizonte, Minas Gerais, Brazil., Barbosa Pinheiro AP; Departamento de Morfologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, 31270-901, Belo Horizonte, Minas Gerais, Brazil., Ribeiro YM; Departamento de Morfologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, 31270-901, Belo Horizonte, Minas Gerais, Brazil., Weber AA; Departamento de Morfologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, 31270-901, Belo Horizonte, Minas Gerais, Brazil., Paes-Leme FO; Laboratório de Aquacultura, Escola de Veterinária, Universidade Federal de Minas Gerais, 31270-901, Belo Horizonte, Minas Gerais, Brazil., Luz RK; Laboratório de Aquacultura, Escola de Veterinária, Universidade Federal de Minas Gerais, 31270-901, Belo Horizonte, Minas Gerais, Brazil., Bazzoli N; Pontifícia Universidade Católica de Minas Gerais, Programa de Pós-graduação em Biologia de Vertebrados, 30535-610, Belo Horizonte, Minas Gerais, Brazil., Rizzo E; Departamento de Morfologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, 31270-901, Belo Horizonte, Minas Gerais, Brazil., Melo RMC; Departamento de Morfologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, 31270-901, Belo Horizonte, Minas Gerais, Brazil. Electronic address: rafaelmelo@icb.ufmg.br.
Jazyk: angličtina
Zdroj: Molecular and cellular endocrinology [Mol Cell Endocrinol] 2020 Jan 15; Vol. 500, pp. 110643. Date of Electronic Publication: 2019 Nov 08.
DOI: 10.1016/j.mce.2019.110643
Abstrakt: Food restriction is part of the life cycle of many fish species; however, nutritional deficiency may negatively influence gametogenesis and gonadal maturation. The aim of this study was to evaluate the effects of food restriction on the spermatogenesis of Nile tilapia. For this, adult males were submitted to starvation and refeeding cycles (alternating periods of starvation and feeding) for 7, 14, 21, and 28 days. After 7 days of starvation, glycaemic and lipid levels were significantly reduced, followed by reduction of plasma testosterone (T) and 11-ketotestosterone (11-KT). In addition, reduced proliferation of spermatogonia and increased apoptosis of spermatocytes, spermatids, and spermatozoa was observed in starvation groups. In the refeeding groups, the sex steroids and the proportion of germ cells had no significant alterations compared to the control group, except for spermatozoa. In this sense, the present study suggests that starvation after 7 days progressively reduces T and 11-TK, resulting in damage to the production of spermatogenic cells, while refeeding may delay spermatogenesis but does not lead to testicular impairment.
(Copyright © 2019 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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