Should we use kidneys from donors with acute kidney injury for renal transplantation?
| Autor: | Chan GC; Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, China., Chow KM; Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, China. |
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| Jazyk: | angličtina |
| Zdroj: | Nephrology (Carlton, Vic.) [Nephrology (Carlton)] 2020 Feb; Vol. 25 (2), pp. 105-115. Date of Electronic Publication: 2019 Dec 09. |
| DOI: | 10.1111/nep.13679 |
| Abstrakt: | The scarcity of donor organs for transplant results in long waiting times for kidney transplantation and low transplant rate worldwide. Utilization of kidneys from donors with acute kidney injury (AKI) is one of the strategies that has attracted attention recently. This article reviewed the outcomes of transplanted renal allografts from donors with acute kidney injury. Key findings about the transplant outcomes included a higher incidence of delayed graft function and primary non function, but respectable outcomes in the context of similar acute rejection rates, and graft function and graft survival. Against this background and with evidence of high mortality for patients remaining on waiting list of transplant, we advocate consideration of AKI donors for kidney transplantation. (© 2019 Asian Pacific Society of Nephrology.) |
| Databáze: | MEDLINE |
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