Autor: |
Picanco-Castro V; Center for Cell-based Therapy CTC, Regional Blood Center of Ribeirão Preto, University of São Paulo , Ribeirão Preto, São Paulo, Brazil., Gonçalves Pereira C; School of Economics, Business Administration and Accounting, University of São Paulo , Ribeirão Preto, São Paulo, Brazil., Swiech K; Center for Cell-based Therapy CTC, Regional Blood Center of Ribeirão Preto, University of São Paulo , Ribeirão Preto, São Paulo, Brazil.; School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo , Ribeirão Preto, Brazil., Ribeiro Malmegrim KC; Center for Cell-based Therapy CTC, Regional Blood Center of Ribeirão Preto, University of São Paulo , Ribeirão Preto, São Paulo, Brazil.; School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo , Ribeirão Preto, Brazil., Tadeu Covas D; Center for Cell-based Therapy CTC, Regional Blood Center of Ribeirão Preto, University of São Paulo , Ribeirão Preto, São Paulo, Brazil., Silveira Porto G; School of Economics, Business Administration and Accounting, University of São Paulo , Ribeirão Preto, São Paulo, Brazil.; Institute of Advanced Studies of the University of São Paulo IEA/USP , Ribeirão Preto, São Paulo, Brazil. |
Abstrakt: |
The purpose of this study is to mine CAR-T patents and therapies under development, to design a landscape of the sector and to understand key therapy segments and their current trends. The study analyzed the entire market, consisting of 1624 patent families and 509 biologics under development, to depict an overview of the CAR-T therapies and their state of the art. Our results showed cutting-edge inventions, the major players, the dynamics of cooperation among institutions, the progress of the therapies' generation over the years and future innovation pathways. CAR-T therapies are transforming the current scenario for cancer treatment, and this study reveals the picture of what we can likely expect ahead in order to assist scientists at the academy and industry to improve their research strategies. |