Are Community Acquired Respiratory Viral Infections an Underestimated Burden in Hematology Patients?

Autor:	Popescu CM; Department of Hematology, Iuliu Hatieganu University of Medicine and Pharmacy, 8 Babes str., 400012 Cluj-Napoca, Romania. popescu.cristian@umfcluj.ro., Ursache AL; University of Agricultural Sciences and Veterinary Medicine, Calea Mănăștur 3-5, 400372 Cluj-Napoca, Romania. aura_ursache@yahoo.com., Feketea G; Department of Hematology, Iuliu Hatieganu University of Medicine and Pharmacy, 8 Babes str., 400012 Cluj-Napoca, Romania. Fechetea.Gabriela@umfcluj.ro., Bocsan C; Department of Pharmacology, Toxicology and Clinical Pharmacology, Iuliu Haţieganu University of Medicine and Pharmacy, 400337 Cluj-Napoca, Romania. bocsan.corina@umfcluj.ro., Jimbu L; Department of Hematology, Iuliu Hatieganu University of Medicine and Pharmacy, 8 Babes str., 400012 Cluj-Napoca, Romania. jimbulaura@yahoo.com., Mesaros O; Department of Hematology, Iuliu Hatieganu University of Medicine and Pharmacy, 8 Babes str., 400012 Cluj-Napoca, Romania. mesaros.oana@umfcluj.ro., Edwards M; Airway Disease Infection Section, National Heart Lung Institute, Imperial College London, London, UK MRC & Asthma UK Centre for Allergic Mechanisms of Asthma, Norfolk Place, W2 1PG London, UK. michael.edwards@imperial.ac.uk., Wang H; School of Medicine, Nanjing University, 22 Hankou Road, 210093 Nanjing, China. hwang@nju.edu.cn., Berceanu I; Department of Hematology, Ion Chiricuta Oncology Institute, 34-36 Republicii Street, 400015 Cluj-Napoca, Romania. iuliaberceanu@yahoo.com., Neaga A; Department of Hematology, Iuliu Hatieganu University of Medicine and Pharmacy, 8 Babes str., 400012 Cluj-Napoca, Romania. Neaga.Alexandra@umfcluj.ro., Zdrenghea M; Department of Hematology, Iuliu Hatieganu University of Medicine and Pharmacy, 8 Babes str., 400012 Cluj-Napoca, Romania. mzdrenghea@umfcluj.ro.; Department of Hematology, Ion Chiricuta Oncology Institute, 34-36 Republicii Street, 400015 Cluj-Napoca, Romania. mzdrenghea@umfcluj.ro.
Jazyk:	angličtina
Zdroj:	Microorganisms [Microorganisms] 2019 Nov 02; Vol. 7 (11). Date of Electronic Publication: 2019 Nov 02.
DOI:	10.3390/microorganisms7110521
Abstrakt:	Despite a plethora of studies demonstrating significant morbidity and mortality due to community-acquired respiratory viral (CRV) infections in intensively treated hematology patients, and despite the availability of evidence-based guidelines for the diagnosis and management of respiratory viral infections in this setting, there is no uniform inclusion of respiratory viral infection management in the clinical hematology routine. Nevertheless, timely diagnosis and systematic management of CRV infections in intensively treated hematology patients has a demonstrated potential to significantly improve outcome. We have briefly summarized the recently published data on CRV infection epidemiology, as well as guidelines on the diagnosis and management of CRV infections in patients intensively treated for hematological malignancies. We have also assessed available treatment options, as well as mentioned novel agents currently in development. Competing Interests: The authors declare no conflict of interest.
Databáze:	MEDLINE
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