Craving and opioid use disorder: A scoping review.

Autor: Kleykamp BA; Department of Anesthesiology, School of Medicine and Dentistry, University of Rochester, USA. Electronic address: Bethea_Kleykamp@URMC.Rochester.edu., De Santis M; National Institute on Drug Abuse, Bethesda, MD, USA., Dworkin RH; Department of Anesthesiology, School of Medicine and Dentistry, University of Rochester, USA., Huhn AS; Behavioral Pharmacology Research Unit, Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD, USA., Kampman KM; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Montoya ID; National Institute on Drug Abuse, Bethesda, MD, USA., Preston KL; Clinical Pharmacology and Therapeutics Research Branch, National Institute on Drug Abuse, Baltimore, MD, USA., Ramey T; National Institute on Drug Abuse, Bethesda, MD, USA., Smith SM; Department of Anesthesiology, School of Medicine and Dentistry, University of Rochester, USA., Turk DC; Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, USA., Walsh R; National Institute on Drug Abuse, Bethesda, MD, USA., Weiss RD; McLean Hospital, Harvard Medical School, Belmont, MA, USA., Strain EC; Behavioral Pharmacology Research Unit, Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Jazyk: angličtina
Zdroj: Drug and alcohol dependence [Drug Alcohol Depend] 2019 Dec 01; Vol. 205, pp. 107639. Date of Electronic Publication: 2019 Oct 17.
DOI: 10.1016/j.drugalcdep.2019.107639
Abstrakt: Introduction: The subjective experience of drug craving is a prominent and common clinical phenomenon for many individuals diagnosed with opioid use disorder (OUD), and could be a valuable clinical endpoint in medication development studies. The purpose of this scoping review is to provide an overview and critical analysis of opioid craving assessments located in the published literature examining OUD.
Method: Studies were identified through a search of PubMed, Embase, and PsychInfo databases and included for review if opioid craving was the focus and participants were diagnosed with or in treatment for OUD.
Results: Fifteen opioid craving assessment instruments were identified across the 87 studies included for review. The most common were the Visual Analog Scale (VAS, 41 studies), Desires for Drug Questionnaire (DDQ, 12 studies), Heroin Craving Questionnaire (HCQ, 10 studies), and Obsessive-Compulsive Drug Use Scale (OCDUS, 10 studies). Craving assessments varied considerably in their format, content, time frame, and underlying subscales, and only 6 of 15 had been psychometrically evaluated.
Discussion: This review identified a variety of opioid craving assessments, but few had been evaluated for their psychometric properties making it difficult to ascertain whether craving is being assessed optimally in studies of OUD. Thus, the development of a reliable and valid opioid craving assessment would be worthwhile and could be guided by recently published Food and Drug Administration Clinical Outcome Assessment (COA) guidelines. Importantly, a COA focused on opioid craving could be a valuable addition to research studies designed to evaluate novel treatments for OUD.
(Copyright © 2019 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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