Effect of Metofluthrin-Impregnated Spatial Repellent Devices Combined with New Long-Lasting Insecticidal Nets (Olyset ® Plus) on Pyrethroid-Resistant Malaria Vectors and Malaria Prevalence: Field Trial in South-Eastern Malawi.

Autor: Kawada H; Department of Vector Ecology and Environment, Institute of Tropical Medicine, Nagasaki University., Nakazawa S; Department of Vector Ecology and Environment, Institute of Tropical Medicine, Nagasaki University., Shimabukuro K; Faculty of Nursing, Nagano College of Nursing., Ohashi K; Health and Crop Sciences Research Laboratory, Sumitomo Chemical Co., Ltd., Kambewa EA; Vector Borne Disease Laboratory, Chancellor College, University of Malawi., Foster Pemba D; Vector Borne Disease Laboratory, Chancellor College, University of Malawi.
Jazyk: angličtina
Zdroj: Japanese journal of infectious diseases [Jpn J Infect Dis] 2020 Mar 24; Vol. 73 (2), pp. 124-131. Date of Electronic Publication: 2019 Oct 31.
DOI: 10.7883/yoken.JJID.2019.311
Abstrakt: Long-lasting insecticidal nets (LLINs) experience some operational problems that reduce their effectiveness, such as limited spaces for hanging, biting of mosquitoes outdoors, a shift of key biting time from midnight to dawn or dusk, and development of pyrethroid resistance in mosquitoes. The concept of spatial repellency may be a countermeasure to overcome the above issues. The effect of the combined use of metofluthrin-impregnated spatial repellent devices (MSRDs) and LLINs (Olyset ® Plus) on malaria prevalence and vector mosquitoes were examined in malaria endemic villages in south-eastern Malawi. The intervention reduced the infection rate in children as well as the number of pyrethroid-resistant vector mosquitoes. To achieve effective malaria control, continued intervention using MSRDs with 2 strips per 10 m 2 at 3-month intervals to reduce the density of malaria mosquitoes is recommended.
Databáze: MEDLINE