Effectiveness of medication review on the number of drug-related problems in patients visiting the outpatient cardiology clinic: A randomized controlled trial.

Autor: Huiskes VJB; Department of Pharmacy, Sint Maartenskliniek, The Netherlands., van den Ende CHM; Department of Rheumatology, Sint Maartenskliniek, The Netherlands., Kruijtbosch M; SIR Institute for Pharmacy Practice and Policy, Leiden, The Netherlands., Ensing HT; Outpatient Pharmacy, Flevoziekenhuis, Almere, The Netherlands., Meijs M; Outpatient Pharmacy, St. Antonius ziekenhuis Nieuwegein, The Netherlands., Meijs VMM; Outpatient Pharmacy, LUMC, Leiden, The Netherlands., Burger DM; Department of pharmacy, Radboud University Medical Center, Nijmegen, The Netherlands., van den Bemt BJF; Department of Pharmacy, Sint Maartenskliniek, The Netherlands.; Department of pharmacy, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Clinical Pharmacy and Toxicology, Maastricht University Medical Center +, Maastricht, The Netherlands.
Jazyk: angličtina
Zdroj: British journal of clinical pharmacology [Br J Clin Pharmacol] 2020 Jan; Vol. 86 (1), pp. 50-61. Date of Electronic Publication: 2019 Dec 03.
DOI: 10.1111/bcp.14125
Abstrakt: Aims: To assess the effectiveness of medication review on the number of drug-related problems (DRPs) in outpatient cardiology patients.
Methods: In this randomized controlled trial, a computer-assisted and pharmacist-led medication review with patient involvement (questionnaire and telephone call with pharmacist) was conducted in intervention patients prior to their visit to the cardiologist. The control group received usual care. Adult outpatient cardiology patients without support concerning the administration of medication, without a medication review in the past 6 months and who gave permission to access their electronic medication record were included. The primary outcome measure was the number of DRPs 1 month after the visit. Secondary outcome measures concerned the type of DRP and the type of medication involved in the DRPs.
Results: In total, 75 patients (mean [standard deviation, SD] age 66.0 [12.5] years, 41% female) were included. Intervention (n = 90) and control group (n = 85) were comparable at baseline. The mean (SD) number of drugs used per patient was 7.9 (3.9). After 1 month, the mean (SD) number of DRPs was 0.3 (0.7) and 0.8 (1.0) and the median (range) number of DRPs was 0 (0-4) and 0 (0-4) in the intervention group and control group, respectively (P < .001). In the intervention group, 74% of the DRPs identified at T0 were solved at T1 vs 14% in the control group.
Conclusion: This randomized controlled trial suggests that a pharmacist-led medication review in patients with a scheduled visit to the outpatient cardiology clinic decreases the number of DRPs.
(© 2019 The British Pharmacological Society.)
Databáze: MEDLINE
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