Successful Treatment of Mycobacterium chelonae Keratitis Within a Corneal Transplant Using Intrastromal Amikacin Injections-A Case Report Demonstrating the Fundamental Principles and Challenges of Infective Keratitis Management and Novel Therapeutic Approaches.

Autor: Merridew NL; Department of Microbiology and Infectious Diseases, Royal Hobart Hospital, Hobart, Australia., Phagura RS; Royal Perth Hospital, Perth, Australia., Anderson E; Department of Pharmacy, Royal Hobart Hospital, Hobart, Australia., Cooley LA; Department of Microbiology and Infectious Diseases, Royal Hobart Hospital, Hobart, Australia., Pollock GA; Centre for Eye Research Australia, The University of Melbourne, Melbourne, Australia., McEwan B; Department of Microbiology and Infectious Diseases, Royal Hobart Hospital, Hobart, Australia., McCartney PJ; Hobart Eye Surgeons, Hobart, Australia., Trad MA; Department of Microbiology and Infectious Diseases, Royal Hobart Hospital, Hobart, Australia.
Jazyk: angličtina
Zdroj: Open forum infectious diseases [Open Forum Infect Dis] 2019 Jul 22; Vol. 6 (8), pp. ofz340. Date of Electronic Publication: 2019 Jul 22 (Print Publication: 2019).
DOI: 10.1093/ofid/ofz340
Abstrakt: Mycobacterium chelonae keratitis is rare and difficult to treat. This is the first known case worldwide of effective treatment using intrastromal amikacin injections in a corneal transplant recipient who had metastatic breast cancer. The challenges and principles of management, applicable to other causes of infective keratitis, are reviewed.
(© The Author(s) 2019. Published by Oxford University Press on behalf of Infectious Diseases Society of America.)
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje