Relation of viscous lidocaine combined with propofol deep sedation during elective upper gastrointestinal endoscopy to discharge.
| Autor: | Ullman DA; Department of Anesthesia, Bassett HealthcareCooperstownNew York.; Department of Anesthesia, Columbia University College of Physicians and SurgeonsNew YorkNew York., Saleem SA; Department of Medicine, Bassett HealthcareCooperstownNew York., Shahnawaz A; Department of Medicine, Bassett HealthcareCooperstownNew York., Kotakanda S; Department of Medicine, Bassett HealthcareCooperstownNew York., Scribani MB; Bassett Healthcare, Bassett Research InstituteCooperstownNew York., Victory JM; Bassett Healthcare, Bassett Research InstituteCooperstownNew York. |
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| Jazyk: | angličtina |
| Zdroj: | Proceedings (Baylor University. Medical Center) [Proc (Bayl Univ Med Cent)] 2019 Jul 30; Vol. 32 (4), pp. 505-509. Date of Electronic Publication: 2019 Jul 30 (Print Publication: 2019). |
| DOI: | 10.1080/08998280.2019.1641058 |
| Abstrakt: | Fusing topical pharyngeal anesthetics (TPAs) to intravenous sedation during esophagogastroduodenoscopy (EGD) has been controversial. This double-blind, randomized, placebo-controlled trial assessed the association of TPA with patient recovery time, post-EGD to discharge. Supplementary aims were to determine the association of TPA with patient and practitioner satisfaction (both measured on a 100-mm visual analog scale), total propofol dose, and side effects. The study included 93 patients (mean age 53.8 years, range 44-67; 37 men and 56 women) undergoing elective EGD at a single academic medical center from September 2015 to October 2016. Urgent or therapeutic EGDs were excluded. Interventions were 7.5 mL 2% lidocaine viscous solution and 7.5 mL placebo solution (3% methylcellulose). There were no statistically significant differences between the lidocaine ( n = 46) and placebo ( n = 47) groups with respect to recovery time (42 ± 17.8 vs 39 ± 15.9 minutes; P = 0.23), procedure time (6.5 ± 2.7 vs 7 ± 3.6 minutes; P = 0.77), endoscopist satisfaction (83.2 ± 24.4 vs 77 ± 27.7, P = 0.23), patient discomfort (16.6 ± 19.8 vs 24.0 ± 29.7, P = 0.37), or total propofol administered (2.3 ± 1.3 vs 2.3 ± 1.0 mg/kg, P = 0.55). Compared to placebo, topical viscous lidocaine does not appear to delay recovery time or adversely affect sedation-related outcomes. (© 2019 Baylor University Medical Center.) |
| Databáze: | MEDLINE |
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