Resilience Against Depression Disparities (RADD): a protocol for a randomised comparative effectiveness trial for depression among predominantly low-income, racial/ethnic, sexual and gender minorities.

Autor:	Vargas SM; Psychology, University of Southern California, Los Angeles, California, USA sylvannv@usc.edu.; Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, UCLA, Los Angeles, California, USA.; Preventive Medicine, University of Southern California, Los Angeles, California, United States., Wennerstrom A; School of Medicine, Tulane University, New Orleans, Louisiana, USA.; LSU Health Sciences Center New Orleans, Louisiana State University, New Orleans, Louisiana, United States., Alfaro N; Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, UCLA, Los Angeles, California, USA., Belin T; Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, UCLA, Los Angeles, California, USA.; Department of Biostatistics, Fielding School of Public Health, UCLA, Los Angeles, California, USA., Griffith K; Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, UCLA, Los Angeles, California, USA., Haywood C; Tulane Prevention Research Center, Tulane University, New Orleans, Louisiana, USA.; Women with a Vision, Inc, New Orleans, Louisiana, USA., Jones F; Healthy African American Families II, Los Angeles, California, USA., Lunn MR; Department of Medicine, Stanford University School of Medicine, Stanford, California, USA.; The PRIDE Study, Stanford University School of Medicine, Stanford, California, United States., Meyers D; Saint Anna's Episcopal Church, New Orleans, Louisiana, USA., Miranda J; Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, UCLA, Los Angeles, California, USA.; Health Policy and Management, Fielding School of Public Health, UCLA, Los Angeles, California, United States., Obedin-Maliver J; Department of Medicine, Stanford University School of Medicine, Stanford, California, USA.; The PRIDE Study, Stanford University School of Medicine, Stanford, California, United States., Pollock M; Section of Community and Population Medicine, Department of Medicine, Louisiana State University School of Medicine, New Orleans, Louisiana, USA., Sherbourne CD; RAND Corporation, Los Angeles, California, USA., Springgate BF; Section of Community and Population Medicine, Department of Medicine, Louisiana State University School of Medicine, New Orleans, Louisiana, USA., Sugarman OK; Section of Community and Population Medicine, Department of Medicine, Louisiana State University School of Medicine, New Orleans, Louisiana, USA.; Center for Health Care Value and Equity, LSU Health Sciences Center, New Orleans, Louisiana, United States.; School of Public Health, LSU Health Sciences Center, New Orleans, California, United States., Rey E; LGBT Community Center, New Orleans, Louisiana, USA.; Let's Hatch Media, New Orleans, Louisiana, USA., Williams C; Healthy African American Families II, Los Angeles, California, USA., Williams P; Healthy African American Families II, Los Angeles, California, USA.; Department of Preventive and Social Medicine, Charles R Drew University of Medicine and Science, Los Angeles, California, USA., Chung B; Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, UCLA, Los Angeles, California, USA.; RAND Corporation, Los Angeles, California, USA.; Department of Psychiatry, Harbor-UCLA Medical Center, Torrance, California, United States.; Department of Mental Health, County of Los Angeles, Los Angeles, California, United States.
Jazyk:	angličtina
Zdroj:	BMJ open [BMJ Open] 2019 Oct 22; Vol. 9 (10), pp. e031099. Date of Electronic Publication: 2019 Oct 22.
DOI:	10.1136/bmjopen-2019-031099
Abstrakt:	Introduction: Depression is the leading cause of adult disability and common among sexual and gender minority (SGM) adults. The current study builds on findings showing the effectiveness of depression quality improvement (QI) and delivery of cognitive behavioural therapy (CBT) skills provided by community health workers in reducing depression. Depression QI approaches across healthcare and social/community services in safety-net settings have shown improvements in mental wellness, mental health quality of life and depression over 12 months. Further, a randomised study showed improved depression among low-income racial/ethnic minorities enrolled in a CBT-informed resiliency class (Building Resilience and Increasing Community Hope (B-RICH)). The current protocol describes a comparativeness effectiveness study to evaluate whether predominantly low-income, SGM racial/ethnic minority adults randomised to a CBT-informed resiliency class have improvements in depressive symptoms over and above community-engaged QI resources and training only. Methods and Analysis: The study approached three clusters of four to five programs serving predominantly SGM and racial/ethnic minority communities in the USA: two clusters in Los Angeles, California, and one in New Orleans, Louisiana. Clusters are comprised of one primary care, one mental health and two to three community agencies (eg, faith-based, social services/support, advocacy). All programs received depression QI training. The current study employed a community-partnered participatory research model to adapt the CBT-informed resiliency class, B-RICH+, to SGM communities. Study participants were screened and recruited in person from participating programs, and will complete baseline, 6- and 12-month survey follow-ups. Participants were depressed adults (8-item Patient Health Questionnaire ≥10; ≥18 years of age) who provided contact information. Enrolled participants were individually randomised to B-RICH+ or depression QI alone. Primary outcomes are depressive symptoms; secondary outcomes are mental health quality of life, mental wellness and physical health quality of life. Data collection for this study is ongoing. Ethics and Dissemination: The current study was approved by the UCLA Institutional Review Board. Study findings will be disseminated through scientific publications and community conferences. Trial Registration Number: https://clinicaltrials.gov/ct2/show/NCT02986126. Competing Interests: Competing interests: None declared. (© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
Databáze:	MEDLINE
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