From molecular to macro: the key role of the apical ligaments in uterovaginal support.

Autor: Kieserman-Shmokler C; University of Michigan Departments of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI. Electronic address: ckieserm@med.umich.edu., Swenson CW; University of Michigan Departments of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI., Chen L; Biomedical Engineering, University of Michigan, Ann Arbor, MI., Desmond LM; Mountain Area Health Education Center, Asheville, NC., Ashton-Miller JA; Mechanical Engineering, University of Michigan, Ann Arbor, MI., DeLancey JO; University of Michigan Departments of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI.
Jazyk: angličtina
Zdroj: American journal of obstetrics and gynecology [Am J Obstet Gynecol] 2020 May; Vol. 222 (5), pp. 427-436. Date of Electronic Publication: 2019 Oct 19.
DOI: 10.1016/j.ajog.2019.10.006
Abstrakt: To explain the pathophysiology of pelvic organ prolapse, we must first understand the complexities of the normal support structures of the uterus and vagina. In this review, we focus on the apical ligaments, which include the cardinal and uterosacral ligaments. The aims of this review are the following: (1) to provide an overview of the anatomy and histology of the ligaments; (2) to summarize the imaging and biomechanical studies of the ligament properties and the way they relate to anterior and posterior vaginal wall prolapse; and (3) to synthesize these findings into a conceptual model for the progression of prolapse.
(Copyright © 2019 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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