Simian Foamy Viruses in Central and South America: A New World of Discovery.

Autor: Santos AF; Departamento de Genética, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-617, RJ, Brazil. andre20@globo.com., Cavalcante LTF; Departamento de Genética, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-617, RJ, Brazil. liliane.tavaresdefaria@gmail.com., Muniz CP; Departamento de Genética, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-617, RJ, Brazil. claudia.muniz16@gmail.com., Switzer WM; Laboratory Branch, Division of HIV/AIDS Prevention, National Center for HIV/AIDS, Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA. bis3@cdc.gov., Soares MA; Departamento de Genética, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-617, RJ, Brazil. masaores@inca.gov.br.; Programa de Oncovirologia, Instituto Nacional de Câncer, Riod e Janeiro, RJ 20231-050, RJ, Brazil. masaores@inca.gov.br.
Jazyk: angličtina
Zdroj: Viruses [Viruses] 2019 Oct 20; Vol. 11 (10). Date of Electronic Publication: 2019 Oct 20.
DOI: 10.3390/v11100967
Abstrakt: Foamy viruses (FVs) are the only exogenous retrovirus to date known to infect neotropical primates (NPs). In the last decade, an increasing number of strains have been completely or partially sequenced, and molecular evolution analyses have identified an ancient co-speciation with their hosts. In this review, the improvement of diagnostic techniques that allowed the determination of a more accurate prevalence of simian FVs (SFVs) in captive and free-living NPs is discussed. Determination of DNA viral load in American primates indicates that oral tissues are the viral replicative site and that buccal swab collection can be an alternative to diagnose SFV infection in NPs. Finally, the transmission potential of NP SFVs to primate workers in zoos and primate centers of the Americas is examined.
Databáze: MEDLINE
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