Fabrication of porphyrin-based magnetic covalent organic framework for effective extraction and enrichment of sulfonamides.

Autor: Zhang J; School of Chemistry and Environmental Engineering, Wuhan Institute of Technology, Wuhan, 430205, China. Electronic address: zhang_juan@wit.edu.cn., Chen Z; School of Chemistry and Environmental Engineering, Wuhan Institute of Technology, Wuhan, 430205, China., Tang S; School of Chemistry and Environmental Engineering, Wuhan Institute of Technology, Wuhan, 430205, China., Luo X; School of Chemical Engineering and Pharmacy, Wuhan Institute of Technology, Wuhan, 430205, China., Xi J; School of Chemistry and Environmental Engineering, Wuhan Institute of Technology, Wuhan, 430205, China., He Z; School of Chemistry and Environmental Engineering, Wuhan Institute of Technology, Wuhan, 430205, China., Yu J; School of Chemistry and Environmental Engineering, Wuhan Institute of Technology, Wuhan, 430205, China. Electronic address: yujunxia_1979@163.com., Wu F; School of Chemical Engineering and Pharmacy, Wuhan Institute of Technology, Wuhan, 430205, China. Electronic address: wfs42@126.com.
Jazyk: angličtina
Zdroj: Analytica chimica acta [Anal Chim Acta] 2019 Dec 16; Vol. 1089, pp. 66-77. Date of Electronic Publication: 2019 Aug 29.
DOI: 10.1016/j.aca.2019.08.066
Abstrakt: The dehydration reaction of tetraamino porphyrin and 4,4'-biphenyldicarboxaldehyde was performed for the synthesis of a novel covalent organic framework (COF), which was decorated on magnetic Fe 3 O 4 to obtain core-shell structured Fe 3 O 4 @COFs nanospheres for the first time, for effective extraction and enrichment of sulfonamides (SAs). The morphology and structure of the synthesized nanospheres were characterized through various methods. The extraction conditions for six SAs including sulfadiazine, sulfamerazine, sulfamethazine, sulfamonomethoxine, sulfamethoxazole, sulfadimethoxine were systematically optimized. Fe 3 O 4 @COFs nanospheres were evaluated for magnetic solid-phase extraction. By coupling with high-performance liquid chromatography, a facile and sensitive method was established for the quantitation analysis of six SAs. The method showed good linearity ranging from 1 to 500 ng mL -1 with R 2  > 0.99, high sensitivity with LODs in the range of 0.2-1 ng mL -1 , and high precision with RSDs≤6.3%. This method was further applied into determination of SAs in environmental water and food samples, with recoveries in the range of 65.3%-107.3% and RSDs≤6.7%. These successful applications suggest that the core-shell structured Fe 3 O 4 @COFs nanospheres could be used as a potential adsorbent for efficient extraction and analysis of trace SAs.
(Copyright © 2019 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: