| Autor: |
Dreval AV; Moscows regional research clinical institute n.a. M.F. Vladimirskiy., Tsub AF; Medical Research Radiological Center of the Russian Academy of Medical Sciences., Nechayeva OA; Moscows regional research clinical institute n.a. M.F. Vladimirskiy., Komerdus IV; Moscows regional research clinical institute n.a. M.F. Vladimirskiy., Drozdovsky BY; Medical Research Radiological Center of the Russian Academy of Medical Sciences., Garbuzov PI; Medical Research Radiological Center of the Russian Academy of Medical Sciences., Guseva TN; Medical Research Radiological Center of the Russian Academy of Medical Sciences. |
| Jazyk: |
ruština |
| Zdroj: |
Problemy endokrinologii [Probl Endokrinol (Mosk)] 2007 Apr 15; Vol. 53 (2), pp. 45-48. Date of Electronic Publication: 2007 Apr 15. |
| DOI: |
10.14341/probl200753245-48 |
| Abstrakt: |
Forty-eight patients with diffuse toxic goiter (Graves's disease) were treated with radioactive iodine in a dose of 5.3-30.0 mCi. A special formula considering the volume of the thyroid and post-24-hour capture of the diagnostic activity of radioactive iodine was used to calculate the optimum therapeutic activity. As a result, specific therapeutic activity (STA) correlated with specific activity and with the volume of thyroid. The high rate (33.3%) of recurrent thyrotoxicosis was observed when the calculated STA was less than 0 3 mCi/ml and reduced to 11.1% if a greater activity was applied. The use of the standard activity of radioactive iodine (10mCi) with a thyroid volume of up to 40 ml, as compared to that calculated by the formula results in the similar rate of ineffective radioiodine therapy for thyrotoxicosis at a lower incidence of euthyrosis. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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