[Neuroanatomical brain profile of juvenile shiftlike schizophrenia: morphometry of grey matter in the prefrontal cortex and subcortical structures].

Autor:	Kaleda VG; Mental Health Research Center, Moscow, Russia., Bozjko OV; Mental Health Research Center, Moscow, Russia., Akhadov TA; Research Institute of emergency child surgery and traumatology, Moscow, Russia., Tomyshev AS; Mental Health Research Center, Moscow, Russia., Tikhonov DV; Mental Health Research Center, Moscow, Russia., Lebedeva IS; Mental Health Research Center, Moscow, Russia., Savvateeva NY; Mental Health Research Center, Moscow, Russia.
Jazyk:	ruština
Zdroj:	Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova [Zh Nevrol Psikhiatr Im S S Korsakova] 2019; Vol. 119 (8), pp. 7-11.
DOI:	10.17116/jnevro20191190817
Abstrakt:	Aim: To determine neuroanatomical peculiarities of grey matter in some regions of the prefrontal cortex and several subcortical structures in patients with juvenile shift like schizophrenia (F20 ICD-10). Material and Methods: Forty-three young male patients and 54 mentally healthy men without family history of mental diseases underwent structural MRI with T1 high resolution images. Results: As compared to mentally healthy subjects, there was a decrease of grey matter thickness in all tested regions of the prefrontal cortex in patients. No between-group differences in subcortical structures volumes were found. No correlations between structural changes and psychopathological symptoms were observed. Conclusion: Structural abnormalities of the frontal lobes in juvenile shift like schizophrenia are not associated with severity of psychopathological symptoms.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu