Unusual presentation of a disseminated oral HPV infection after combined antiretroviral therapy initiation.

Autor:	Vale DAD; Universidade de São Paulo, Faculdade de Odontologia, Departamento de Estomatologia, São Paulo, São Paulo, Brazil., Ferracini LMA; Universidade de São Paulo, Faculdade de Odontologia, Departamento de Estomatologia, São Paulo, São Paulo, Brazil., Bueno MVDSR; Universidade de São Paulo, Faculdade de Odontologia, Departamento de Estomatologia, São Paulo, São Paulo, Brazil., Souza ACMF; Universidade de São Paulo, Instituto de Medicina Tropical de São Paulo, Laboratório de Virologia (LIM 52), São Paulo, São Paulo, Brazil., Braz-Silva PH; Universidade de São Paulo, Faculdade de Odontologia, Departamento de Estomatologia, São Paulo, São Paulo, Brazil.; Universidade de São Paulo, Instituto de Medicina Tropical de São Paulo, Laboratório de Virologia (LIM 52), São Paulo, São Paulo, Brazil., Ortega KL; Universidade de São Paulo, Faculdade de Odontologia, Departamento de Estomatologia, São Paulo, São Paulo, Brazil.
Jazyk:	angličtina
Zdroj:	Revista do Instituto de Medicina Tropical de Sao Paulo [Rev Inst Med Trop Sao Paulo] 2019 Oct 10; Vol. 61, pp. e54. Date of Electronic Publication: 2019 Oct 10 (Print Publication: 2019).
DOI:	10.1590/S1678-9946201961054
Abstrakt:	HPV clinical manifestations have their characteristics modified by the use of combined antiretroviral therapy (cART), although its incidence is unaffected by cART. We report an unusual presentation of oral HPV infection and discuss an effective treatment for disseminated HPV lesions. A 52-year-old male of Asian-origin, HIV-seropositive, presented with extensive nodular lesions throughout the oral mucosa extending to the oropharyngeal region. Biopsy followed by histopathological examination and HPV genotyping were performed. The treatment was initiated with topical application of podophyllin and trichloroacetic acid. HPV lesions in oral mucosa are generally easy to handle. Extensive lesions can make it difficult to choose an effective treatment that meets the patient's particularities and medication availability.
Databáze:	MEDLINE
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