Biocompatibility in regenerative nanomedicine.

Autor: Zor F; Department of Surgery, Wake Forest University Health Sciences, Wake Forest Institute for Regenerative Medicine, Winston-Salem, NC 27101, USA., Selek FN; Department of Surgery, Wake Forest University Health Sciences, Wake Forest Institute for Regenerative Medicine, Winston-Salem, NC 27101, USA., Orlando G; Section of Transplantation, Department of Surgery, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA., Williams DF; Wake Forest School of Medicine, Wake Forest Institute for Regenerative Medicine, Winston-Salem, NC 27101, USA.
Jazyk: angličtina
Zdroj: Nanomedicine (London, England) [Nanomedicine (Lond)] 2019 Oct; Vol. 14 (20), pp. 2763-2775. Date of Electronic Publication: 2019 Oct 15.
DOI: 10.2217/nnm-2019-0140
Abstrakt: Biocompatibility is a very common word that is used within biomaterial science and used for description of the interactions between the foreign material and the body. However, the meaning of biocompatibility as well as the mechanisms that collectively constitutes is still unclear. With the advance of nanotechnology, new concerns have been observed related to biocompatibility of these biomaterials. Due to their small size and variability of their physical and chemical properties, nanoparticles' (NP) distribution within the body and interactions with the target cells and tissues are highly variable. Here, we tried to provide an overview about NPs, the concept of biocompatibility and biocompatibility-related issues in nanomedicine and several different NPs.
Databáze: MEDLINE