Imaging Patterns of Toxic and Metabolic Brain Disorders.

Autor:	de Oliveira AM; From the Neuroradiology Section, Institute of Radiology, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP), R Dr Ovídio Pires de Campos 75, São Paulo, SP 05403-010, Brazil (A.M.d.O., M.V.P., G.T.d.S., C.d.C.L., L.F.d.S.G., L.T.L.); Neuroradiology Section, Department of Radiology, Hospital Sirio-Libanês, São Paulo, Brazil (A.P.F.V.); Neuroradiology Division, Department of Radiology, University of Minnesota Medical Center, Minneapolis, Minn (A.M.M.); and Division of Neuroradiology, Santa Casa de São Paulo School of Medical Sciences, São Paulo, Brazil (A.J.d.R.)., Paulino MV; From the Neuroradiology Section, Institute of Radiology, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP), R Dr Ovídio Pires de Campos 75, São Paulo, SP 05403-010, Brazil (A.M.d.O., M.V.P., G.T.d.S., C.d.C.L., L.F.d.S.G., L.T.L.); Neuroradiology Section, Department of Radiology, Hospital Sirio-Libanês, São Paulo, Brazil (A.P.F.V.); Neuroradiology Division, Department of Radiology, University of Minnesota Medical Center, Minneapolis, Minn (A.M.M.); and Division of Neuroradiology, Santa Casa de São Paulo School of Medical Sciences, São Paulo, Brazil (A.J.d.R.)., Vieira APF; From the Neuroradiology Section, Institute of Radiology, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP), R Dr Ovídio Pires de Campos 75, São Paulo, SP 05403-010, Brazil (A.M.d.O., M.V.P., G.T.d.S., C.d.C.L., L.F.d.S.G., L.T.L.); Neuroradiology Section, Department of Radiology, Hospital Sirio-Libanês, São Paulo, Brazil (A.P.F.V.); Neuroradiology Division, Department of Radiology, University of Minnesota Medical Center, Minneapolis, Minn (A.M.M.); and Division of Neuroradiology, Santa Casa de São Paulo School of Medical Sciences, São Paulo, Brazil (A.J.d.R.)., McKinney AM; From the Neuroradiology Section, Institute of Radiology, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP), R Dr Ovídio Pires de Campos 75, São Paulo, SP 05403-010, Brazil (A.M.d.O., M.V.P., G.T.d.S., C.d.C.L., L.F.d.S.G., L.T.L.); Neuroradiology Section, Department of Radiology, Hospital Sirio-Libanês, São Paulo, Brazil (A.P.F.V.); Neuroradiology Division, Department of Radiology, University of Minnesota Medical Center, Minneapolis, Minn (A.M.M.); and Division of Neuroradiology, Santa Casa de São Paulo School of Medical Sciences, São Paulo, Brazil (A.J.d.R.)., da Rocha AJ; From the Neuroradiology Section, Institute of Radiology, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP), R Dr Ovídio Pires de Campos 75, São Paulo, SP 05403-010, Brazil (A.M.d.O., M.V.P., G.T.d.S., C.d.C.L., L.F.d.S.G., L.T.L.); Neuroradiology Section, Department of Radiology, Hospital Sirio-Libanês, São Paulo, Brazil (A.P.F.V.); Neuroradiology Division, Department of Radiology, University of Minnesota Medical Center, Minneapolis, Minn (A.M.M.); and Division of Neuroradiology, Santa Casa de São Paulo School of Medical Sciences, São Paulo, Brazil (A.J.d.R.)., Dos Santos GT; From the Neuroradiology Section, Institute of Radiology, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP), R Dr Ovídio Pires de Campos 75, São Paulo, SP 05403-010, Brazil (A.M.d.O., M.V.P., G.T.d.S., C.d.C.L., L.F.d.S.G., L.T.L.); Neuroradiology Section, Department of Radiology, Hospital Sirio-Libanês, São Paulo, Brazil (A.P.F.V.); Neuroradiology Division, Department of Radiology, University of Minnesota Medical Center, Minneapolis, Minn (A.M.M.); and Division of Neuroradiology, Santa Casa de São Paulo School of Medical Sciences, São Paulo, Brazil (A.J.d.R.)., Leite CDC; From the Neuroradiology Section, Institute of Radiology, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP), R Dr Ovídio Pires de Campos 75, São Paulo, SP 05403-010, Brazil (A.M.d.O., M.V.P., G.T.d.S., C.d.C.L., L.F.d.S.G., L.T.L.); Neuroradiology Section, Department of Radiology, Hospital Sirio-Libanês, São Paulo, Brazil (A.P.F.V.); Neuroradiology Division, Department of Radiology, University of Minnesota Medical Center, Minneapolis, Minn (A.M.M.); and Division of Neuroradiology, Santa Casa de São Paulo School of Medical Sciences, São Paulo, Brazil (A.J.d.R.)., Godoy LFS; From the Neuroradiology Section, Institute of Radiology, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP), R Dr Ovídio Pires de Campos 75, São Paulo, SP 05403-010, Brazil (A.M.d.O., M.V.P., G.T.d.S., C.d.C.L., L.F.d.S.G., L.T.L.); Neuroradiology Section, Department of Radiology, Hospital Sirio-Libanês, São Paulo, Brazil (A.P.F.V.); Neuroradiology Division, Department of Radiology, University of Minnesota Medical Center, Minneapolis, Minn (A.M.M.); and Division of Neuroradiology, Santa Casa de São Paulo School of Medical Sciences, São Paulo, Brazil (A.J.d.R.)., Lucato LT; From the Neuroradiology Section, Institute of Radiology, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo (HC-FMUSP), R Dr Ovídio Pires de Campos 75, São Paulo, SP 05403-010, Brazil (A.M.d.O., M.V.P., G.T.d.S., C.d.C.L., L.F.d.S.G., L.T.L.); Neuroradiology Section, Department of Radiology, Hospital Sirio-Libanês, São Paulo, Brazil (A.P.F.V.); Neuroradiology Division, Department of Radiology, University of Minnesota Medical Center, Minneapolis, Minn (A.M.M.); and Division of Neuroradiology, Santa Casa de São Paulo School of Medical Sciences, São Paulo, Brazil (A.J.d.R.).
Jazyk:	angličtina
Zdroj:	Radiographics : a review publication of the Radiological Society of North America, Inc [Radiographics] 2019 Oct; Vol. 39 (6), pp. 1672-1695.
DOI:	10.1148/rg.2019190016
Abstrakt:	Toxic and metabolic brain disorders are relatively uncommon diseases that affect the central nervous system, but they are important to recognize as they can lead to catastrophic outcomes if not rapidly and properly managed. Imaging plays a key role in determining the most probable diagnosis, pointing to the next steps of investigation, and providing prognostic information. The majority of cases demonstrate bilateral and symmetric involvement of structures at imaging, affecting the deep gray nuclei, cortical gray matter, and/or periventricular white matter, and some cases show specific imaging manifestations. When an appropriate clinical situation suggests exogenous or endogenous toxic effects, the associated imaging pattern usually indicates a restricted group of diagnostic possibilities. Nonetheless, toxic and metabolic brain disorders in the literature are usually approached in the literature by starting with common causal agents and then reaching imaging abnormalities, frequently mixing many different possible manifestations. Conversely, this article proposes a systematic approach to address this group of diseases based on the most important imaging patterns encountered in clinical practice. Each pattern is suggestive of a most likely differential diagnosis, which more closely resembles real-world scenarios faced by radiologists. Basic pathophysiologic concepts regarding cerebral edemas and their relation to imaging are introduced-an important topic for overall understanding. The most important imaging patterns are presented, and the main differential diagnosis for each pattern is discussed. Online supplemental material is available for this article. © RSNA, 2019.
Databáze:	MEDLINE
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