Chronic Kidney Disease and Coronary Artery Disease: JACC State-of-the-Art Review.

Autor:	Sarnak MJ; Division of Nephrology, Tufts Medical Center, Boston, Massachusetts. Electronic address: msarnak@tuftsmedicalcenter.org., Amann K; Department of Nephropathology, University Hospital Erlangen, Erlangen, Germany., Bangalore S; Division of Cardiology, New York University School of Medicine, New York, New York., Cavalcante JL; Minneapolis Heart Institute, Minneapolis, Minnesota., Charytan DM; Division of Nephrology, New York University School of Medicine, New York, New York., Craig JC; College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia., Gill JS; Division of Nephrology, St. Paul's Hospital, University of British Columbia, Vancouver, British Columbia, Canada., Hlatky MA; Department of Health Research and Policy, Stanford University School of Medicine, Stanford, California., Jardine AG; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, United Kingdom., Landmesser U; Department of Cardiology, Charité Universitätsmedizin, Berlin, Germany., Newby LK; Division of Cardiology, Department of Medicine and Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina., Herzog CA; Division of Cardiology, Department of Medicine, Hennepin County Medical Center and University of Minnesota, Minneapolis, Minnesota; Chronic Disease Research Group, Minneapolis Medical Research Foundation, Minneapolis, Minnesota., Cheung M; Kidney Disease: Improving Global Outcomes, Brussels, Belgium., Wheeler DC; University College London, London, United Kingdom., Winkelmayer WC; Selzman Institute for Kidney Health, Section of Nephrology, Department of Medicine, Baylor College of Medicine, Houston, Texas., Marwick TH; Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia. Electronic address: tom.marwick@baker.edu.au.
Jazyk:	angličtina
Zdroj:	Journal of the American College of Cardiology [J Am Coll Cardiol] 2019 Oct 08; Vol. 74 (14), pp. 1823-1838.
DOI:	10.1016/j.jacc.2019.08.1017
Abstrakt:	Chronic kidney disease (CKD) is a major risk factor for coronary artery disease (CAD). As well as their high prevalence of traditional CAD risk factors, such as diabetes and hypertension, persons with CKD are also exposed to other nontraditional, uremia-related cardiovascular disease risk factors, including inflammation, oxidative stress, and abnormal calcium-phosphorus metabolism. CKD and end-stage kidney disease not only increase the risk of CAD, but they also modify its clinical presentation and cardinal symptoms. Management of CAD is complicated in CKD patients, due to their likelihood of comorbid conditions and potential for side effects during interventions. This summary of the Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference on CAD and CKD (including end-stage kidney disease and transplant recipients) seeks to improve understanding of the epidemiology, pathophysiology, diagnosis, and treatment of CAD in CKD and to identify knowledge gaps, areas of controversy, and priorities for research. (Copyright © 2019 The Authors. Published by Elsevier Inc. All rights reserved.)
Databáze:	MEDLINE
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