Association of Irisin Serum Concentration and Muscle Strength in Normal-Weight and Overweight Young Women.

Autor: Martínez Muñoz IY; School of Medicine, Autonomous University of Mexico State, Toluca, Mexico., Camarillo Romero EDS; School of Medicine, Autonomous University of Mexico State, Toluca, Mexico.; School of Chemistry, Autonomous University of Mexico State, Toluca, Mexico., Correa Padilla T; School of Chemistry, Autonomous University of Mexico State, Toluca, Mexico., Santillán Benítez JG; School of Chemistry, Autonomous University of Mexico State, Toluca, Mexico., Camarillo Romero MDS; School of Chemistry, Autonomous University of Mexico State, Toluca, Mexico., Montenegro Morales LP; School of Chemistry, Autonomous University of Mexico State, Toluca, Mexico., Bravo GGH; School of Medicine, Autonomous University of Mexico State, Toluca, Mexico., Garduño García JJ; School of Medicine, Autonomous University of Mexico State, Toluca, Mexico.; Regional General Hospital No. 251, Mexican Institute of Social Security, Toluca, Mexico.
Jazyk: angličtina
Zdroj: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2019 Sep 13; Vol. 10, pp. 621. Date of Electronic Publication: 2019 Sep 13 (Print Publication: 2019).
DOI: 10.3389/fendo.2019.00621
Abstrakt: Background: Irisin is a muscle-contraction-induced myokine. In previous studies, it has been related to exercise type, fitness and physical activity; however, evidence is not consistent. Thus, the aim of this study was to research the association between health-related fitness and irisin in young women. Methods: The study was designed as a prospective cross-sectional one. Young, healthy, nonsmoking women were enlisted. The sample comprised 40 overweight (OW) and 40 normal-weight (NW) individuals. The average age was 18.63 ± 0.63 and 18.78 ± 0.73 years, respectively. Components of health-related fitness, metabolic parameters, serum irisin and body composition were analyzed. Results: Statistically significant differences were found in physical tests between NW and OW groups for one-leg standing, hand grip strength, vertical jump, modified push-up, fitness index and maximal oxygen uptake (VO 2MAX ). There were no differences in concentrations of serum irisin between the groups. We found a positive correlation between irisin and hand grip strength ( r = 0.374, p = 0.023). In a multivariate analysis adjusted by body fat, a significant association between irisin and hand grip strength was observed in OW group (β = 0.380, p = 0.026); as well, a positive association between irisin and one-leg standing test in NW group (β = 0.311, p = 0.044) was found. Conclusions: According to our findings, hand grip strength could be linked to irisin concentration in overweight young women.
(Copyright © 2019 Martínez Muñoz, Camarillo Romero, Correa Padilla, Santillán Benítez, Camarillo Romero, Montenegro Morales, Huitrón Bravo and Garduño García.)
Databáze: MEDLINE
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