Genetic diversity of respiratory enteroviruses and rhinoviruses in febrile adults, Singapore, 2007-2013.

Autor: Linster M; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore., Donato C; Department of Microbiology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia., Mah MG; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore., Grau ML; Department of Microbiology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia., Low JG; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore., Ooi EE; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore., Su YCF; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore., Smith GJD; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.; Duke Global Health Institute, Duke University, Durham, North Carolina., Vijaykrishna D; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.; Department of Microbiology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.
Jazyk: angličtina
Zdroj: Influenza and other respiratory viruses [Influenza Other Respir Viruses] 2020 Jan; Vol. 14 (1), pp. 67-71. Date of Electronic Publication: 2019 Sep 30.
DOI: 10.1111/irv.12662
Abstrakt: To understand the genetic diversity and patterns of circulation of rhinoviruses (RV) and enteroviruses (EV) in Singapore, we retrospectively screened 2950 nasal swab samples collected from adults presenting to primary care services with signs of febrile illness in Singapore during 2007-2013 using sequencing and phylogenetic methods. Through sequencing and phylogenetic analysis, our results show the year-round circulation of the three rhinovirus species, A, B, and C. A diverse set of RV/EV serotypes were detected in Singapore with a predominance of RV-A in all years, whereas serotypes EV-C A21 and EV-D68 were only sporadically detected. This study highlights the previously unrecognized diversity and burden in the adult population in Singapore.
(© 2019 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
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