British Society of Gastroenterology consensus guidelines on the management of inflammatory bowel disease in adults.

Autor: Lamb CA; Newcastle University, Newcastle upon Tyne, UK.; Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, UK., Kennedy NA; Royal Devon and Exeter NHS Foundation Trust, Exeter, UK.; University of Exeter, Exeter, UK., Raine T; Cambridge University Hospitals NHS FoundationTrust, Cambridge, UK., Hendy PA; Chelsea and Westminster Hospital NHS Foundation Trust, London, UK.; Imperial College London, London, UK., Smith PJ; Royal Liverpool and Broadgreen University Hospitals NHS Trust, Liverpool, UK., Limdi JK; The Pennine Acute Hospitals NHS Trust, Manchester, UK.; University of Manchester, Manchester, UK., Hayee B; King's College Hospital NHS Foundation Trust, London, UK.; King's College London, London, UK., Lomer MCE; King's College London, London, UK.; Guy's and St Thomas' NHS Foundation Trust, London, UK., Parkes GC; Barts Health NHS Trust, London, UK.; Barts and the London School of Medicine and Dentistry, London, UK., Selinger C; Leeds Teaching Hospitals NHS Trust, Leeds, UK.; University of Leeds, Leeds, UK., Barrett KJ; New Road Surgery, Rickmansworth, UK., Davies RJ; Cambridge University Hospitals NHS FoundationTrust, Cambridge, UK.; University of Cambridge, Cambridge, UK., Bennett C; Systematic Research Ltd, Quorn, UK.; Royal College of Surgeons in Ireland (RCSI), Dublin, Ireland., Gittens S; ECD Solutions, Bridgetown, Barbados., Dunlop MG; University of Edinburgh, Edinburgh, UK.; Western General Hospital, Edinburgh, UK., Faiz O; Imperial College London, London, UK.; St Mark's Hospital, Harrow, UK., Fraser A; University Hospitals Bristol NHS Foundation Trust, Bristol, UK., Garrick V; Royal Hospital for Children Glasgow, Glasgow, UK., Johnston PD; Crohn's and Colitis UK, Hatfield, UK., Parkes M; Cambridge University Hospitals NHS FoundationTrust, Cambridge, UK., Sanderson J; King's College London, London, UK.; Guy's and St Thomas' NHS Foundation Trust, London, UK., Terry H; Crohn's and Colitis UK, Hatfield, UK., Gaya DR; Glasgow Royal Infirmary, Glasgow, UK.; University of Glasgow, Glasgow, UK., Iqbal TH; Queen Elizabeth Hospital Birmingham NHSFoundation Trust, Birmingham, UK.; University of Birmingham, Birmingham, UK., Taylor SA; University College London, London, UK.; University College London Hospitals NHS Foundation Trust, London, UK., Smith M; Brighton and Sussex University Hospitals NHS Trust, Brighton, UK.; Brighton and Sussex Medical School, Brighton, UK., Brookes M; Royal Wolverhampton NHS Trust, Wolverhampton, UK.; University of Wolverhampton, Wolverhampton, UK., Hansen R; Royal Hospital for Children Glasgow, Glasgow, UK.; University of Glasgow, Glasgow, UK., Hawthorne AB; University Hospital of Wales, Cardiff, UK.
Jazyk: angličtina
Zdroj: Gut [Gut] 2019 Dec; Vol. 68 (Suppl 3), pp. s1-s106. Date of Electronic Publication: 2019 Sep 27.
DOI: 10.1136/gutjnl-2019-318484
Abstrakt: Ulcerative colitis and Crohn's disease are the principal forms of inflammatory bowel disease. Both represent chronic inflammation of the gastrointestinal tract, which displays heterogeneity in inflammatory and symptomatic burden between patients and within individuals over time. Optimal management relies on understanding and tailoring evidence-based interventions by clinicians in partnership with patients. This guideline for management of inflammatory bowel disease in adults over 16 years of age was developed by Stakeholders representing UK physicians (British Society of Gastroenterology), surgeons (Association of Coloproctology of Great Britain and Ireland), specialist nurses (Royal College of Nursing), paediatricians (British Society of Paediatric Gastroenterology, Hepatology and Nutrition), dietitians (British Dietetic Association), radiologists (British Society of Gastrointestinal and Abdominal Radiology), general practitioners (Primary Care Society for Gastroenterology) and patients (Crohn's and Colitis UK). A systematic review of 88 247 publications and a Delphi consensus process involving 81 multidisciplinary clinicians and patients was undertaken to develop 168 evidence- and expert opinion-based recommendations for pharmacological, non-pharmacological and surgical interventions, as well as optimal service delivery in the management of both ulcerative colitis and Crohn's disease. Comprehensive up-to-date guidance is provided regarding indications for, initiation and monitoring of immunosuppressive therapies, nutrition interventions, pre-, peri- and postoperative management, as well as structure and function of the multidisciplinary team and integration between primary and secondary care. Twenty research priorities to inform future clinical management are presented, alongside objective measurement of priority importance, determined by 2379 electronic survey responses from individuals living with ulcerative colitis and Crohn's disease, including patients, their families and friends.
Competing Interests: Competing interests: Conflicts of interest for authors and contributors are presented in online supplementary table 2.
(© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
Databáze: MEDLINE