[The synopsis of clinical cytometry: acute megakaryoblastic leukemia.]

Autor:	Illarionova OI; The Dmitrii Rogachev Federal research clinical center of children hematology, oncology and immunology of Minzdrav of Russia, 117997, Moscow, Russia., Gorchakova MV; The academician I.P. Pavlov First St. Petersburg state medical university, laboratory of clinical immunology and molecular diagnostic, 197022, St. Petersburg, Russia., Rusanova EB; The academician I.P. Pavlov First St. Petersburg state medical university, laboratory of clinical immunology and molecular diagnostic, 197022, St. Petersburg, Russia., Prokhorova YA; The academician I.P. Pavlov First St. Petersburg state medical university, laboratory of clinical immunology and molecular diagnostic, 197022, St. Petersburg, Russia., Salogub GN; The academician I.P. Pavlov First St. Petersburg state medical university, chair of faculty therapy, 197022, St. Petersburg, Russia., Osipova EY; The Dmitrii Rogachev Federal research clinical center of children hematology, oncology and immunology of Minzdrav of Russia, 117997, Moscow, Russia., Plyasunova SA; The Dmitrii Rogachev Federal research clinical center of children hematology, oncology and immunology of Minzdrav of Russia, 117997, Moscow, Russia., Zueva EE; The academician I.P. Pavlov First St. Petersburg state medical university, the research methodical center of molecular medicine, 197022, St. Petersburg, Russia.; The Ariel University, Faculty of natural sciences, molecular biology dep., 40700, Ariel, Israel.
Jazyk:	ruština
Zdroj:	Klinicheskaia laboratornaia diagnostika [Klin Lab Diagn] 2015; Vol. 60 (7), pp. 42-49.
DOI:	10.18821/0860-2084-2015-60-7-42-49
Abstrakt:	The acute megakaryoblastic leukemia is a rather rare form of pathology even in practice of specialized oncological hematological departments. The data of cytometry analysis of 2363 patients monitored from 2007 to 2014 carried out in The Dmitrii Rogachev Federal research clinical center of children hematology, oncology and immunology and The academician I.P. Pavlov First St. Petersburg state medical university was used to diagnose acute megakaryoblastic leukemia. The corresponding diagnosis was established in 24 patients of various age categories, including 16 children (11 boys and 5 girls) and 8 adults (ratio male/female 1:1). The trisomy on chromosome 21 was revealed only in 4 children out of 13 of early age (younger than 3 years). The article describes characteristics of samples taking preparation and interpretation of data of multicolor with regard to experience of national and foreign colleges. Competing Interests: The authors declare no conflict of interest.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu