[The laboratory markers of early metabolic disorders in workers of rubber Articles industry.]

Autor:	Timasheva GV; The Ufa research institute of occupational medicine and human ecology, the Republic of Bashkortostan, Ufa, Russia., Bakirov AB; The Ufa research institute of occupational medicine and human ecology, the Republic of Bashkortostan, Ufa, Russia., Valeeva ET; The Ufa research institute of occupational medicine and human ecology, the Republic of Bashkortostan, Ufa, Russia., Karimova LK; The Ufa research institute of occupational medicine and human ecology, the Republic of Bashkortostan, Ufa, Russia., Masiagutova LM; The Ufa research institute of occupational medicine and human ecology, the Republic of Bashkortostan, Ufa, Russia.
Jazyk:	ruština
Zdroj:	Klinicheskaia laboratornaia diagnostika [Klin Lab Diagn] 2015; Vol. 60 (7), pp. 31-35.
DOI:	10.18821/0860-2084-2015-60-7-31-35
Abstrakt:	The article presents results of complex laboratory analyses applied to workers of rubber articles industry using biochemical, hematological, immunological techniques. The study established the most expressed and early alterations of processes of oxidative metabolism (decreasing of catalase activity, increasing of level of malonic dialdehyde and uric acid) and indicators of lipid metabolism of blood serum. The increasing of percentage of persons with metabolic disorders related to length of service in industry is established. In examined workers signs of anemia (erythropenia, decreasing of level of hemoglobin) and leukopenia were detected. The imbalance of T-cell component (CD+ CD4+), accompanied by alteration of phagocyte activity and defect of humoral component with increasing of level of IgM and decreasing of level of IgA. The coefficients of diagnostic sensitivity of analyzed laboratory tests were established. The most significant laboratory markers permit diagnosing early metabolic disorders and degree of their expressiveness in workers of rubber articles industry. Competing Interests: The authors declare no conflict of interest.
Databáze:	MEDLINE
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