[Clinical value of transient elastography (FibroScan) in detection of clonorchiasis].

Autor:	Bin Z; Guangxi Medical University, Nanning 530023, China., Jian-Lin W; Guangxi Medical University, Nanning 530023, China., Xiao-Lin W; Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention, China., Guo-Li L; Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention, China., Wen-Qian T; Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention, China., Zhi-Hua J; Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention, China.
Jazyk:	čínština
Zdroj:	Zhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control [Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi] 2019 Jun 26; Vol. 31 (3), pp. 319-322.
DOI:	10.16250/j.32.1374.2019004
Abstrakt:	Objective: To assess the clinical significance of transient elastography (Fibroscan) in detection of clonorchiasis, so as to provide new insights into the assessment of therapeutic efficacy of deworming. Methods: The liver stiffness measurement (LSM) values were measured in parasitologically diagnosed clonorchiasis patients using FibroScan before and after deworming, and the patients'age, gender, body mass index (BMI), duration of raw fish consumption and total amount of raw fish consumption were collected for correlation analyses. Results: The clonorchiasis patients'age, gender, BMI, duration of raw fish consumption and total amount of raw fish consumption had no associations with pre-treatment LSM values ( r / r s = 0.189, 0.073, 0.180; 0.071, -0.098, 0.033; 0.166, 0.309, 0.172; 0.235, 0.247, 0.209; 0.164, 0.277, 0.088; all P values > 0.05). There was a significant difference in the LSM values from the seventh, eighth and ninth intercostal space prior to deworming ( F = 3.259, P < 0.05), and no significant difference was detected after deworming ( F = 0.851, P > 0.05). The LSM values from the seventh, eighth and ninth intercostal space were significantly lower pre-deworming than post-deworming ( t = 6.724, 5.603, 2.884; all P values < 0.05). Conclusions: FibroScan is feasible to assess the therapuetic efficacy of deworming in patients with clonorchiasis; however, measurement at various sites affects the LSM value.
Databáze:	MEDLINE
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