Leptospirosis: Increasing importance in developing countries.

Autor: Soo ZMP; Department of Biological Sciences, School of Science and Technology, Sunway University, Selangor, Malaysia., Khan NA; Department of Biology, Chemistry and Environmental Sciences, College of Arts and Sciences, American University of Sharjah, University City, Sharjah, United Arab Emirates. Electronic address: nkhan@aus.edu., Siddiqui R; Department of Biology, Chemistry and Environmental Sciences, College of Arts and Sciences, American University of Sharjah, University City, Sharjah, United Arab Emirates.
Jazyk: angličtina
Zdroj: Acta tropica [Acta Trop] 2020 Jan; Vol. 201, pp. 105183. Date of Electronic Publication: 2019 Sep 19.
DOI: 10.1016/j.actatropica.2019.105183
Abstrakt: Leptospirosis is a zoonotic disease caused by the pathogenic helical spirochetes, Leptospira. Symptoms include sudden-onset fever, severe headaches, muscle pain, nausea and chills. Leptospirosis is endemic in developing countries such as Malaysia, India, Sri Lanka, and Brazil where thousands of cases are reported annually. The disease risk factors include the high population of reservoirs, environmental factors, recreational factors, and occupational factors. To end the endemicity of leptospirosis, these factors need to be tackled. The management of leptospirosis needs to be refined. Early diagnosis remains a challenge due to a lack of clinical suspicion among physicians, its non-specific symptoms and a limited availability of rapid point-of-care diagnostic tests. The purpose of this review is to provide insight into the status of leptospirosis in developing countries focusing on the risk factors and to propose methods for the improved management of the disease.
(Copyright © 2019 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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