Diagnosis and management of Guillain-Barré syndrome in ten steps.

Autor: Leonhard SE; Department of Neurology, Erasmus University Medical Center, Rotterdam, Netherlands., Mandarakas MR; Department of Neurology, Erasmus University Medical Center, Rotterdam, Netherlands., Gondim FAA; Hospital Universitário Walter Cantidio, Universidade Federal do Ceará, Fortaleza, Ceará, Brazil., Bateman K; Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa., Ferreira MLB; Department of Neurology, Hospital da Restauração, Recife, Pernambuco, Brazil., Cornblath DR; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., van Doorn PA; Department of Neurology, Erasmus University Medical Center, Rotterdam, Netherlands., Dourado ME; Department of Integrative Medicine, Hospital Universitário Onofre Lopes, Universidade Federal do Rio Grande do Norte, Natal, Brazil., Hughes RAC; UCL Queen Square Institute of Neurology, University College London, London, UK., Islam B; International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh., Kusunoki S; Kindai University Faculty of Medicine, Osaka, Japan., Pardo CA; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Reisin R; Hospital Británico, Buenos Aires, Argentina., Sejvar JJ; Centers for Disease Control and Prevention, Atlanta, GA, USA., Shahrizaila N; Department of Neurology, University of Malaya, Kuala Lumpur, Malaysia., Soares C; Hospital Federal dos Servidores do Estado, Rio de Janeiro, Brazil., Umapathi T; National Neuroscience Institute, Singapore, Singapore., Wang Y; Department of Neurology, Affiliated Hospital of Jining Medical University, Jining, Shandong, China., Yiu EM; Department of Neurology, The Royal Children's Hospital Melbourne, Melbourne, VIC, Australia.; Neurosciences Research, Murdoch Children's Research Institute, Melbourne, VIC, Australia.; Department of Paediatrics, The University of Melbourne, Melbourne, VIC, Australia., Willison HJ; College of Medicine, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK., Jacobs BC; Department of Neurology, Erasmus University Medical Center, Rotterdam, Netherlands. b.jacobs@erasmusmc.nl.; Department of Immunology, Erasmus University Medical Center, Rotterdam, Netherlands. b.jacobs@erasmusmc.nl.
Jazyk: angličtina
Zdroj: Nature reviews. Neurology [Nat Rev Neurol] 2019 Nov; Vol. 15 (11), pp. 671-683. Date of Electronic Publication: 2019 Sep 20.
DOI: 10.1038/s41582-019-0250-9
Abstrakt: Guillain-Barré syndrome (GBS) is a rare, but potentially fatal, immune-mediated disease of the peripheral nerves and nerve roots that is usually triggered by infections. The incidence of GBS can therefore increase during outbreaks of infectious diseases, as was seen during the Zika virus epidemics in 2013 in French Polynesia and 2015 in Latin America. Diagnosis and management of GBS can be complicated as its clinical presentation and disease course are heterogeneous, and no international clinical guidelines are currently available. To support clinicians, especially in the context of an outbreak, we have developed a globally applicable guideline for the diagnosis and management of GBS. The guideline is based on current literature and expert consensus, and has a ten-step structure to facilitate its use in clinical practice. We first provide an introduction to the diagnostic criteria, clinical variants and differential diagnoses of GBS. The ten steps then cover early recognition and diagnosis of GBS, admission to the intensive care unit, treatment indication and selection, monitoring and treatment of disease progression, prediction of clinical course and outcome, and management of complications and sequelae.
Databáze: MEDLINE
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