[qSOFA score for prediction of outcome in surgical patients in intensive care units. Post hoc analysis of the Russian multi-center trial Rises].

Autor:	Astafieva MN; Municipal Clinical Hospital №40, Yekaterinburg, Russia; Ural State Medical University of the Ministry of healthcare of the Russia, Yekaterinburg, Russia, Rudnov VA; Municipal Clinical Hospital №40, Yekaterinburg, Russia; Ural State Medical University of the Ministry of healthcare of the Russia, Yekaterinburg, Russia, Kulabukhov VV; Vishnevsky National Medical Research Center of Surgery, Moscow, Russia, Bagin VA; Municipal Clinical Hospital №40, Yekaterinburg, Russia; Ural State Medical University of the Ministry of healthcare of the Russia, Yekaterinburg, Russia, Zubareva NA; Vagner Perm State Medical University of the Ministry of healthcare of the Russia, Perm, Russia, Tribulyov MA; Municipal Clinical Hospital №4, Perm, Russia, Mukhacheva SY; Tyumen State Medical University of the Ministry of healthcare of the Russia, Tyumen, Russia
Jazyk:	ruština
Zdroj:	Khirurgiia [Khirurgiia (Mosk)] 2019 (9), pp. 58-65.
DOI:	10.17116/hirurgia201909158
Abstrakt:	Objective: To define the informative value of qSOFA score in the prediction of outcomes in surgical patients admitted to the Intensive Care Units. Study Design: Post hoc analysis of multicenter prospective observational study RISES. The following patient information was analyzed: gender, age, diagnosis, presence of infection, SIRS criteria, qSOFA and SOFA scores, outcomes. Results: The study included data of 331 patients with surgical diseases. Infection was not observed in 174 (52.6%) cases, 157 (47.4%) patients had infection. In the group of patients without infection, area under ROC-curve for SIRS criteria was 0.519 (95% CI 0.429-0.610) and similar to that qSOFA (p=0.535). Area under ROC-curve for SOFA scale was 0.619 (95% CI 0.511-0.726) and did not significantly differ from this value for QSOFA (p=0.241). In the group of surgical patients with infection, area under ROC-curve for SIRS was 0.490 (95% CI 0.419-0.561), that was significantly lower than area under ROC-curve for qSOFA (p=0.016). Area under ROC-curve for SOFA scale was 0.803 (95% CI 0.681-0.924), that significantly exceeded area under ROC-curve for qSOFA (p=0.017). Conclusion: qSOFA scale is important in surgical patients with infection admitted to ICUs. Increased qSOFA score is associated with augmentation of mortality rate. qSOFA scale significantly exceeds the SIRS criteria, but is inferior to the SOFA in the prognosis of mortality in these patients.
Databáze:	MEDLINE
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