Pellagra and anorexia nervosa: a case report.

Autor: Portale S; Laboratory of Dietetics and Clinical Nutrition, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Via Bassi 21, 27100, Pavia, PV, Italy. sandra.portale@gmail.com., Sculati M; Department of Public Health, Experimental and Forensic Medicine, Master Course in Dietetics and Clinical Nutrition, University of Pavia, Via Bassi 21, 27100, Pavia, PV, Italy., Stanford FC; Department of Medicine-Neuroendocrine Division, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA, 02114, USA.; Department of Pediatrics-Endocrinology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA, 02114, USA., Cena H; Laboratory of Dietetics and Clinical Nutrition, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Via Bassi 21, 27100, Pavia, PV, Italy.; Clinical Nutrition and Dietetics Service, Unit of Internal Medicine and Endocrinology, ICS Maugeri IRCCS, Via S.Maugeri 10, 27100, Pavia, PV, Italy.
Jazyk: angličtina
Zdroj: Eating and weight disorders : EWD [Eat Weight Disord] 2020 Oct; Vol. 25 (5), pp. 1493-1496. Date of Electronic Publication: 2019 Sep 17.
DOI: 10.1007/s40519-019-00781-x
Abstrakt: Background: While pellagra appears to be a rare entity currently, it may still develop. It is important to recognize how the disease manifests to ensure adequate and timely treatment.
Case Presentation: We present a case of pellagra secondary to anorexia nervosa in a 28-year-old woman. We observed the classical signs: erythema in the neck region, diarrhea, and neurologic symptoms. Diagnosis was made on a clinical basis, and the patient had a rapid recovery after undergoing therapy with nicotinamide and tryptophan.
Conclusions: In our case, the patient did not exhibit any sign of being severely underweight with marked malnutrition such as the typical manifestation expected in pellagra. This case demonstrated that clinicians should have a high level of suspicion in making a diagnosis of pellagra, especially in patients with a history of eating disorders.
Level of Evidence: IV (case study).
Databáze: MEDLINE
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