Giant dumbbell C2C3 neurofibroma invading prebulbar cistern: Case report and literature review.

Autor:	Serrano JPM; Department of Neurology, Pontifical Catholic University of Sorocaba, Sorocaba, São Paulo, Brazil., Neves MWF; Department of Postgraduate Studies, State Public Server of São Paulo Hospital, São Paulo, Brazil., Marchi C; Department of Neurosurgery, Santa Paula Hospital, São Paulo, Brazil., Nakasone FJ; Department of Neurosurgery, Santa Paula Hospital, São Paulo, Brazil., Maldaun MVC; Department of Neurosurgery, Santa Paula Hospital, São Paulo, Brazil., de Aguiar PHP; Department of Neurology, Pontifical Catholic University of Sorocaba, Sorocaba, São Paulo, Brazil.; Department of Postgraduate Studies, State Public Server of São Paulo Hospital, São Paulo, Brazil.; Department of Neurosurgery, Santa Paula Hospital, São Paulo, Brazil., Scappini W Jr; Specialist Neurophysiologist-Clinical, São Paulo, Brazil.
Jazyk:	angličtina
Zdroj:	Surgical neurology international [Surg Neurol Int] 2019 May 10; Vol. 10, pp. 77. Date of Electronic Publication: 2019 May 10 (Print Publication: 2019).
DOI:	10.25259/SNI-76-2019
Abstrakt:	Background: Neurofibromatosis 1 (NF1) has a broad spectrum of clinical manifestations, most typically involving café-au-lait spots and skin neurofibromas. Only 2% of patients with NF1 have symptomatic spinal tumors. Case Description: A patient with a previous diagnosis of NF1 presented with cervicalgia, dysphagia/mild dysphonia, gait alteration, and progressive hypoesthesia involving all four limbs. The magnetic resonance documented a giant dumbbell neurofibroma arising between the C2 and C3 levels which extended toward the foramen magnum, causing medullary and bulbar compression. The major challenge of surgical management was the enormous size and location this C2-C3 (5 cm × 4 cm × 5.1 cm) lesion. Conclusions: Compression of the foramen magnum attributed to a dumbbell giant spinal neurofibroma at the C2C3 level resulting in prebulbar cisterns should be among the differential diagnostic considerations for patients presenting with tetraparesis and underlying NF1. Competing Interests: There are no conflicts of interest.
Databáze:	MEDLINE
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