| Autor: |
García-Arenzana N; Preventive Medicine Department, La Paz University Hospital, Madrid, Spain., Redondo-Bravo L; Preventive Medicine Department, La Paz University Hospital, Madrid, Spain., Espinel-Ruiz MA; Preventive Medicine Department, La Paz University Hospital, Madrid, Spain., Borrego-Prieto P; Preventive Medicine Department, La Paz University Hospital, Madrid, Spain., Ruiz-Carrascoso G; Microbiology Department, La Paz University Hospital, Madrid, Spain., Quintas-Viqueira A; Preventive Medicine Department, La Paz University Hospital, Madrid, Spain., Sanchez-Calles A; Preventive Medicine Department, La Paz University Hospital, Madrid, Spain., Robustillo-Rodela A; Preventive Medicine Department, La Paz University Hospital, Madrid, Spain. |
| Jazyk: |
angličtina |
| Zdroj: |
Microbial drug resistance (Larchmont, N.Y.) [Microb Drug Resist] 2020 Jan; Vol. 26 (1), pp. 54-59. Date of Electronic Publication: 2019 Sep 16. |
| DOI: |
10.1089/mdr.2018.0390 |
| Abstrakt: |
Introduction: Carbapenem-resistant Enterobacteriaceae (CRE) are a growing public health problem. We describe an outbreak by CRE and the measures to control it in a hospitalization unit in Spain. Methods: In June 2015, the system of prevention and control of CRE implemented in the hospital detected an increase in the incidence of patients with CRE in a mixed hospitalization facility (geriatrics, internal medicine, and pneumology), with the appearance of four related patients in 2 weeks, three of them being nosocomial cases. A multidisciplinary group was created and carried out: weekly screenings, general cleaning, four training sessions for personnel, two hand hygiene observation studies and environmental sampling. A higher incidence of new cases was detected in three adjoining rooms, in which environmental decontamination was performed with vaporized hydrogen peroxide. Results: In 5 months, a total of 18 cases were detected, 14 of them were nosocomial. Four different clones of Klebsiella pneumoniae OXA-48 were responsible for 83.3% of the cases. Adherence to hand hygiene increased from 36% to 85% after the training sessions. Seven percent of the environmental samples were positive for CRE in rooms with high incidence, moving to 0% after decontamination with hydrogen peroxide. Three patients died, one of them possibly associated with clinical infection due to CRE. Conclusions: Multidisciplinary information strategies, personnel training, and control of environmental reservoirs are effective to address outbreaks of CRE. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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