Systemic bleeding including pulmonary haemorrhage following hump-nosed pit viper (Hypnale hypnale) envenoming: A case report from Sri Lanka.

Autor: Rathnayaka RMMKN; Intensive Care Unit, Teaching Hospital, Ratnapura, Sri Lanka; Department of Veterinary Pathobiology, Faculty of Veterinary Medicine and Animal Science, University of Peradeniya, Sri Lanka; Postgraduate Institute of Medicine (Clinical Pharmacology and Therapeutics), University of Colombo, Sri Lanka. Electronic address: namalrath10@yahoo.com., Ranathunga PEAN; Medical Unit, Teaching Hospital, Ratnapura, Sri Lanka., Kularatne SAM; Department of Medicine, Faculty of Medicine, University of Peradeniya, Sri Lanka.
Jazyk: angličtina
Zdroj: Toxicon : official journal of the International Society on Toxinology [Toxicon] 2019 Dec; Vol. 170, pp. 21-28. Date of Electronic Publication: 2019 Sep 09.
DOI: 10.1016/j.toxicon.2019.09.009
Abstrakt: Out of seven venomous land snake species of Sri Lanka, hump-nosed pit viper (Hypnale spp.) causes the commonest venomous snakebites. It is widely distributed all over the country except in the peninsula of Jaffna. The genus has three species naming H. hypnale, H. zara and H. nepa. They frequently cause local envenoming and rarely cause coagulopathy and acute kidney injury. Systemic bleeding is the most trivial complication associated with coagulopathy caused by these snakes and pulmonary haemorrhages are one of them which are rarely reported. Antivenoms are currently not available for genus Hypnale bites in Sri Lanka. We describe a fatal case of pulmonary haemorrhage caused by a proven hump-nosed viper (Hypnale hypnale) bite associated with other systemic bleeding manifestations and thrombotic microangiopathy. This is the first known case of pulmonary and intracranial haemorrhages caused by hump-nosed viper bite.
(Copyright © 2019 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE