| Autor: |
Rappocciolo E; Department of Biology and Biochemistry, Faculty of Science, Birzeit University, Ramallah, Palestine., Stiban J; Department of Biology and Biochemistry, Faculty of Science, Birzeit University, Ramallah, Palestine. jstiban@birzeit.edu. |
| Jazyk: |
angličtina |
| Zdroj: |
Advances in experimental medicine and biology [Adv Exp Med Biol] 2019; Vol. 1159, pp. 5-31. |
| DOI: |
10.1007/978-3-030-21162-2_2 |
| Abstrakt: |
Mitochondria and bacteria share a myriad of properties since it is believed that the powerhouses of the eukaryotic cell have evolved from a prokaryotic origin. Ribosomal RNA sequences, DNA architecture and metabolism are strikingly similar in these two entities. Proteins and nucleic acids have been a hallmark for comparison between mitochondria and prokaryotes. In this chapter, similarities (and differences) between mitochondrial and prokaryotic membranes are addressed with a focus on structure-function relationship of different lipid classes. In order to be suitable for the theme of the book, a special emphasis is reserved to the effects of bioactive sphingolipids, mainly ceramide, on mitochondrial membranes and their roles in initiating programmed cell death. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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