Predictors of symptomatic lymphocele after kidney transplantation.

Autor: Joosten M; Department of Vascular and Transplant Surgery, Radboudumc, Postbus 9101, 6500 HB, Nijmegen, The Netherlands., d'Ancona FC; Department of Urology, Radboudumc, Nijmegen, The Netherlands., van der Meijden WA; Department of Nephrology, Radboudumc, Nijmegen, The Netherlands., Poyck PP; Department of Vascular and Transplant Surgery, Radboudumc, Postbus 9101, 6500 HB, Nijmegen, The Netherlands. paul.poyck@radboudumc.nl.
Jazyk: angličtina
Zdroj: International urology and nephrology [Int Urol Nephrol] 2019 Dec; Vol. 51 (12), pp. 2161-2167. Date of Electronic Publication: 2019 Sep 05.
DOI: 10.1007/s11255-019-02269-0
Abstrakt: Purpose: The development of a symptomatic lymphocele (SL) is a frequent postoperative surgical complication after kidney transplantation. It may lead to pain and discomfort and cause transplant malfunction or even secondary graft loss. A large cohort of renal recipients was investigated to identify the possible risk factors for SL.
Methods: All renal transplant patients of a single centre were retrospectively analysed for SL between January 2010 and December 2017. The SL group was compared to a control group from the same cohort.
Results: 45 out of 1003 transplanted patients developed an SL (incidence 4.5%), on average 50 days after kidney transplantation. SLs developed more in older patients, in those with a PD catheter and in ADKDP as primary diagnosis. Surgical predictors for SLs were venous anastomosis on the external iliac vein, concomitant PD catheter removal, perfusion defects, shorter operating time, splint > 7 days, double J stenting, discharge with drain, low initial drain production and ureteral obstruction. Opening of the peritoneum, re-operation for postoperative bleeding and previous nephrectomy seem protective for developing SL.
Conclusion: We found multiple heterogeneous predictors for SL with a common denominator related to surgical management of the retroperitoneal space, peritoneum and the ureter. Future prospective studies are necessary to evaluate the influence of these variables on the development of SL.
Databáze: MEDLINE
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